• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

Treatment-associated decline in JAK2V617F allele burden in polycythemia vera: What does it mean?

作者信息

Tefferi Ayalew, Pardanani Animesh, Gangat Naseema

机构信息

Division of Hematology, Department of Medicine, Mayo Clinic, Rochester, Minnesota, USA.

出版信息

Am J Hematol. 2024 Aug;99(8):1459-1461. doi: 10.1002/ajh.27375. Epub 2024 May 20.

DOI:10.1002/ajh.27375
PMID:38767433
Abstract
摘要

相似文献

1
Treatment-associated decline in JAK2V617F allele burden in polycythemia vera: What does it mean?真性红细胞增多症中与治疗相关的JAK2V617F等位基因负荷下降：这意味着什么？
Am J Hematol. 2024 Aug;99(8):1459-1461. doi: 10.1002/ajh.27375. Epub 2024 May 20.
2
Association of JAK2V617F allele burden and clinical correlates in polycythemia vera: a systematic review and meta-analysis.JAK2V617F 等位基因负担与真性红细胞增多症临床相关性的系统评价和荟萃分析。
Ann Hematol. 2024 Jun;103(6):1947-1965. doi: 10.1007/s00277-024-05754-4. Epub 2024 Apr 23.
3
Congenital JAK2V617F polycythemia vera: where does the genotype-phenotype diversity end?先天性JAK2V617F真性红细胞增多症：基因型-表型多样性的终点在哪里？
Blood. 2008 Nov 15;112(10):4356-7. doi: 10.1182/blood-2008-08-175620.
4
Data-driven analysis of the kinetics of the JAK2V617F allele burden and blood cell counts during hydroxyurea treatment of patients with polycythemia vera, essential thrombocythemia, and primary myelofibrosis.基于数据的动力学分析：羟基脲治疗真性红细胞增多症、原发性血小板增多症和原发性骨髓纤维化患者时 JAK2V617F 等位基因负担和血细胞计数的变化。
Eur J Haematol. 2021 Dec;107(6):624-633. doi: 10.1111/ejh.13700. Epub 2021 Sep 30.
5
Postimatinib therapy emergence of a new JAK2V617F clone and subsequent development of overt polycythemia vera in a patient with chronic myelogenous leukaemia.伊马替尼治疗后慢性粒细胞白血病患者出现新的JAK2V617F克隆并随后发展为明显的真性红细胞增多症。
Eur J Haematol. 2010 Jul;85(1):86-7. doi: 10.1111/j.1600-0609.2010.01458.x. Epub 2010 Apr 16.
6
Impact of JAK2V617F Mutation Burden on Disease Phenotype in Chinese Patients with JAK2V617F-positive Polycythemia Vera (PV) and Essential thrombocythemia (ET).JAK2V617F突变负荷对中国JAK2V617F阳性真性红细胞增多症（PV）和原发性血小板增多症（ET）患者疾病表型的影响
Int J Med Sci. 2016 Jan 25;13(1):85-91. doi: 10.7150/ijms.10539. eCollection 2016.
7
Ruxolitinib reduces JAK2 p.V617F allele burden in patients with polycythemia vera enrolled in the RESPONSE study.在参与RESPONSE研究的真性红细胞增多症患者中，鲁索替尼可降低JAK2 p.V617F等位基因负荷。
Ann Hematol. 2017 Jul;96(7):1113-1120. doi: 10.1007/s00277-017-2994-x. Epub 2017 Apr 30.
8
Coexistence of gain-of-function JAK2 germ line mutations with JAK2V617F in polycythemia vera.真性红细胞增多症中功能获得性JAK2种系突变与JAK2V617F的共存。
Blood. 2016 Nov 3;128(18):2266-2270. doi: 10.1182/blood-2016-04-711283. Epub 2016 Sep 19.
9
The JAK2V617 mutation induces constitutive activation and agonist hypersensitivity in basophils from patients with polycythemia vera.JAK2V617 突变诱导真性红细胞增多症患者嗜碱性粒细胞的组成性激活和激动剂超敏反应。
Haematologica. 2009 Nov;94(11):1537-45. doi: 10.3324/haematol.2009.007047. Epub 2009 Jul 16.
10
Non-driver mutations in patients with JAK2V617F-mutated polycythemia vera or essential thrombocythemia with long-term molecular follow-up.对JAK2V617F突变的真性红细胞增多症或原发性血小板增多症患者进行长期分子随访中的非驱动突变
Ann Hematol. 2018 Mar;97(3):443-451. doi: 10.1007/s00277-017-3193-5. Epub 2017 Nov 27.

引用本文的文献

1
Survey of Clinical Practice in Chronic Myeloproliferative Neoplasms in Croatia: A Study by the MPN Working Group Party of the Croatian Cooperative Group for Hematologic Diseases (KROHEM).克罗地亚慢性骨髓增殖性肿瘤临床实践调查：克罗地亚血液疾病合作组（KROHEM）MPN 工作组的一项研究
J Clin Med. 2025 Feb 24;14(5):1524. doi: 10.3390/jcm14051524.
2
Hematologic and molecular responses to ropeginterferon alfa-2b therapy of polycythemia vera: 48-week results from a prospective study.真性红细胞增多症患者接受聚乙二醇干扰素α-2b治疗的血液学和分子学反应：一项前瞻性研究的48周结果
Int J Cancer. 2025 Aug 1;157(3):526-533. doi: 10.1002/ijc.35411. Epub 2025 Mar 15.