Department of Nuclear Medicine, the Ningde Municipal Hospital of Ningde Normal University, Ningde.
Clin Nucl Med. 2024 Aug 1;49(8):790-792. doi: 10.1097/RLU.0000000000005289. Epub 2024 May 14.
A 53-year-old man with newly diagnosed nasopharyngeal carcinoma (NPC) underwent 99m Tc-MDP bone scintigraphy for the potential bone metastases, and paired 68 Ga-DOTATATE and 68 Ga-FAPI PET/CT for initial staging. 68 Ga-DOTATATE PET/CT identified 2 abnormal foci with increased tracer uptake in the cervical vertebra and the ilium, whereas 68 Ga-FAPI PET/CT and bone scan detected only the ilium lesion. A subsequent biopsy confirmed NPC metastasis in the ilium. Furthermore, baseline and follow-up bone scintigraphy revealed that the positive lesion in the cervical vertebra, as indicated in 68 Ga-DOTATATE PET/CT, was also a bone metastasis. This case highlighted the potential superiority of 68 Ga-DOTATATE in NPC.
一位 53 岁男性被诊断为鼻咽癌（NPC），进行 99mTc-MDP 骨扫描以排除骨转移的可能，并进行 68Ga-DOTATATE 和 68Ga-FAPI PET/CT 进行初始分期。68Ga-DOTATATE PET/CT 发现颈椎和髂骨有 2 个异常摄取放射性示踪剂的焦点，而 68Ga-FAPI PET/CT 和骨扫描仅发现髂骨病变。随后的活检证实了髂骨的 NPC 转移。此外，基线和随访骨扫描显示，68Ga-DOTATATE PET/CT 所示颈椎的阳性病变也是骨转移。该病例突出了 68Ga-DOTATATE 在 NPC 中的潜在优势。
