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创伤后迟发性面瘫:2 例报告及系统评价。

Post-traumatic Delayed Facial Nerve Palsy: Report of 2 Cases and Systematic Review.

机构信息

Department of Neuroscience DNS, Otolaryngology Section, University of Padua, Padua, Italy.

Department of Neuroscience DNS, Phoniatrics and Audiology Unit, University of Padua, Treviso, Italy.

出版信息

Otolaryngol Head Neck Surg. 2024 Oct;171(4):990-999. doi: 10.1002/ohn.829. Epub 2024 May 20.

Abstract

OBJECTIVE

Delayed facial nerve palsy (dFNP) secondary to head injury is definitely uncommon. Although the mechanism of immediate facial nerve paralysis is well-studied, its delayed presentation remains debated. Given the dearth of available information, we reported herein our experience with 2 cases of posttraumatic dFNP. This systematic review aimed to evaluate all available information on dFNP and to assess treatment outcome also comparing conservatively and surgically approaches.

DATA SOURCES

Pubmed, Scopus, and Web of Science databases were systematically screened.

REVIEW METHODS

The protocol of this investigation was registered on PROSPERO in April 2023 and the systematic review was performed according to the Preferred Reporting Items for Systematic Reviews and Meta-analyses statement.

RESULTS

Both patients in the case studies showed a complete recovery within 2 to 3 months after the head trauma. One of them still reported a subjective taste alteration at last control. After the application of the inclusion-exclusion criteria, 9 manuscripts with adequate relevance to this topic were included in the systematic review. The study population consisted of 1971 patients with a diagnosis of posttraumatic facial nerve palsy, of which 128 with a dFNP.

CONCLUSIONS

dFNP due to head trauma is a rarely encountered clinical entity, and optimal treatment still remains to be elucidated. Based on the reported data, it seems rational to propose a conservative approach for dFNP with steroid administration as a first line in most cases, indicating surgery in severe and/or refractory cases.

摘要

目的

外伤性迟发性面神经麻痹(dFNP)继发于头部损伤的情况肯定不常见。尽管即时性面神经麻痹的机制已经得到了充分的研究,但它的迟发性表现仍存在争议。鉴于可用信息的缺乏,我们在此报告了我们对 2 例外伤性迟发性面神经麻痹的经验。本系统评价旨在评估所有关于 dFNP 的可用信息,并评估治疗结果,同时比较保守和手术方法。

数据来源

系统地筛选了 Pubmed、Scopus 和 Web of Science 数据库。

审查方法

本研究的方案于 2023 年 4 月在 PROSPERO 上注册,系统评价根据系统评价和荟萃分析的首选报告项目进行。

结果

病例研究中的 2 名患者在头部外伤后 2 至 3 个月内完全恢复。其中 1 名患者在最后一次随访时仍报告有主观味觉改变。在应用纳入和排除标准后,有 9 篇与该主题相关的文献被纳入系统评价。研究人群包括 1971 例外伤性面神经麻痹患者,其中 128 例为迟发性面神经麻痹。

结论

外伤性迟发性面神经麻痹是一种罕见的临床实体,最佳治疗方法仍有待阐明。根据报告的数据,对于 dFNP,建议采用类固醇治疗作为大多数情况下的一线治疗,对于严重和/或难治性病例则考虑手术,这似乎是合理的。

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