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传染性支气管炎病毒:“鸡冠状病毒”概述。

Infectious bronchitis virus: an overview of the "chicken coronavirus".

机构信息

Avian Virology, Animal and Plant Health Agency (APHA)-Weybridge, Woodham Lane, Addlestone, KT15 3NB, UK.

WOAH/FAO International Reference Laboratory for Avian Influenza, Animal and Plant Health Agency (APHA-Weybridge), Woodham Lane, Addlestone, Surrey KT15 3NB, UK.

出版信息

J Med Microbiol. 2024 May;73(5). doi: 10.1099/jmm.0.001828.

Abstract

Infectious bronchitis virus (IBV) is a highly contagious avian that affects mainly chickens () but can circulate in other avian species. IBV constitutes a significant threat to the poultry industry, causing reduced egg yield, growth and mortality levels that can vary in impact. The virus can be transmitted horizontally by inhalation or direct/indirect contact with infected birds or contaminated fomites, vehicles, farm personnel and litter (Figure 1). The error-prone viral polymerase and recombination mechanisms mean diverse viral population results, with multiple genotypes, serotypes, pathotypes and protectotypes. This significantly complicates control and mitigation strategies based on vigilance in biosecurity and the deployment of vaccination.

摘要

传染性支气管炎病毒(IBV)是一种高度传染性的禽类病原体,主要感染鸡(),但也可以在其他禽类物种中传播。IBV 对家禽业构成重大威胁,导致产蛋量下降、生长和死亡率水平受到不同程度的影响。该病毒可以通过吸入或直接/间接接触感染的鸟类或受污染的媒介物、车辆、农场人员和垫料(图 1)进行水平传播。易错的病毒聚合酶和重组机制导致了多种病毒群体的结果,包括多个基因型、血清型、病原型和保护型。这极大地增加了基于生物安全警惕性和疫苗接种部署的控制和缓解策略的复杂性。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9974/11184965/b5c724d1f76a/jmm-73-01828-g001.jpg

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