Knight C D, Allen M J, Nagorney D M, Wold L E, DiMagno E P
Mayo Clin Proc. 1985 Nov;60(11):772-5. doi: 10.1016/s0025-6196(12)60419-4.
Duodenal duplication cysts are rare malformations that characteristically manifest with intestinal obstruction. In a 50-year experience, we found a duodenal duplication cyst in only three patients, one of whom had massive gastrointestinal bleeding as the initial symptom. Six other duplication cysts (two esophageal, one jejunal, and three ileal) were found. All patients who had extraduodenal intestinal cysts were neonates or infants who initially had an abdominal mass or obstruction. Of the two patients with an esophageal cyst, one had odynophagia and the other had respiratory obstruction. Unusual features of our series of patients were male preponderance (eight of nine patients), the low incidence of other developmental abnormalities, and, in the patients with the duodenal cysts, an age of 14 years or older at the time of onset of symptoms and diagnosis. In an adult, a duodenal duplication cyst may cause upper gastrointestinal hemorrhage. This cause of gastrointestinal bleeding should be considered in the differential diagnosis if an intramural duodenal mass is detected within the medial wall of the second portion of the duodenum distal to the papilla of Vater.
十二指肠重复囊肿是一种罕见的畸形,典型表现为肠梗阻。在50年的经验中,我们仅在3例患者中发现了十二指肠重复囊肿,其中1例以大量胃肠道出血为首发症状。还发现了另外6个重复囊肿(2个食管囊肿、1个空肠囊肿和3个回肠囊肿)。所有患有十二指肠外肠囊肿的患者均为新生儿或婴儿,最初表现为腹部肿块或梗阻。在2例食管囊肿患者中,1例有吞咽痛,另1例有呼吸梗阻。我们这组患者的不寻常特征包括男性占多数(9例患者中有8例)、其他发育异常的发生率低,以及在十二指肠囊肿患者中,症状出现和诊断时年龄在14岁或以上。在成年人中,十二指肠重复囊肿可能导致上消化道出血。如果在十二指肠第二部内侧壁距 Vater 乳头远端发现壁内十二指肠肿块,则在鉴别诊断中应考虑这种胃肠道出血的原因。