水熊虫：经训练可在面对 DNA 损伤时变得坚韧。
Tardigrades: Trained to be hardy in the face of DNA damage.
机构信息
Center for Genomic Integrity, Institute for Basic Science, UNIST-gil 50, Ulsan 44919, Republic of Korea.
Center for Genomic Integrity, Institute for Basic Science, UNIST-gil 50, Ulsan 44919, Republic of Korea; Department of Biological Sciences, Ulsan National Institute of Science and Technology (UNIST), Ulsan 44919, Republic of Korea; Graduate School for Health Sciences and Technology, Ulsan National Institute of Science and Technology (UNIST), Ulsan 44919, Republic of Korea.
出版信息
Curr Biol. 2024 May 20;34(10):R504-R507. doi: 10.1016/j.cub.2024.04.030.
Tardigrades withstand ionizing irradiation levels ∼500 times higher than humans can tolerate. Two recent papers shed light on how this might be achieved - via the transcriptional induction of DNA repair genes, the induction of a radioprotective DNA-binding protein, and possibly also the heightened capacity of repair proteins.
水熊虫能够承受的电离辐射水平是人类所能承受的水平的约 500 倍。最近的两篇论文揭示了这一现象产生的原因——通过转录诱导 DNA 修复基因、诱导一种具有放射性保护作用的 DNA 结合蛋白，以及可能还有修复蛋白的高能力。
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