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LDSG-Net:一种用于 ICU 住院期间急性低血压发作预测的高效轻量级卷积神经网络。

LDSG-Net: an efficient lightweight convolutional neural network for acute hypotensive episode prediction during ICU hospitalization.

机构信息

Shenzhen Institute of Advanced Technology, Chinese Academy of Sciences, Shenzhen, Guangdong, People's Republic of China.

College of Artificial Intelligence University of Chinese Academy of Sciences, Beijing, People's Republic of China.

出版信息

Physiol Meas. 2024 Jun 5;45(6). doi: 10.1088/1361-6579/ad4e92.

DOI:10.1088/1361-6579/ad4e92
PMID:38772397
Abstract

. Acute hypotension episode (AHE) is one of the most critical complications in intensive care unit (ICU). A timely and precise AHE prediction system can provide clinicians with sufficient time to respond with proper therapeutic measures, playing a crucial role in saving patients' lives. Recent studies have focused on utilizing more complex models to improve predictive performance. However, these models are not suitable for clinical application due to limited computing resources for bedside monitors.. To address this challenge, we propose an efficient lightweight dilated shuffle group network. It effectively incorporates shuffling operations into grouped convolutions on the channel and dilated convolutions on the temporal dimension, enhancing global and local feature extraction while reducing computational load.. Our benchmarking experiments on the MIMIC-III and VitalDB datasets, comprising 6036 samples from 1304 patients and 2958 samples from 1047 patients, respectively, demonstrate that our model outperforms other state-of-the-art lightweight CNNs in terms of balancing parameters and computational complexity. Additionally, we discovered that the utilization of multiple physiological signals significantly improves the performance of AHE prediction. External validation on the MIMIC-IV dataset confirmed our findings, with prediction accuracy for AHE 5 min prior reaching 93.04% and 92.04% on the MIMIC-III and VitalDB datasets, respectively, and 89.47% in external verification.. Our study demonstrates the potential of lightweight CNN architectures in clinical applications, providing a promising solution for real-time AHE prediction under resource constraints in ICU settings, thereby marking a significant step forward in improving patient care.

摘要

急性低血压发作(AHE)是重症监护病房(ICU)中最严重的并发症之一。一个及时且准确的 AHE 预测系统可以为临床医生提供足够的时间来采取适当的治疗措施,对挽救患者生命起着至关重要的作用。最近的研究集中在利用更复杂的模型来提高预测性能。然而,由于床边监测器的计算资源有限,这些模型并不适合临床应用。为了解决这个挑战,我们提出了一种高效的轻量级扩张洗牌分组网络。它有效地将洗牌操作纳入分组卷积和时间维度的扩张卷积中,在减少计算负载的同时,增强了全局和局部特征提取。我们在 MIMIC-III 和 VitalDB 数据集上的基准实验,分别包含 1304 名患者的 6036 个样本和 1047 名患者的 2958 个样本,表明我们的模型在平衡参数和计算复杂度方面优于其他最先进的轻量级 CNN。此外,我们发现利用多个生理信号可以显著提高 AHE 预测的性能。在 MIMIC-IV 数据集上的外部验证证实了我们的发现,AHE 提前 5 分钟的预测精度在 MIMIC-III 和 VitalDB 数据集上分别达到 93.04%和 92.04%,外部验证达到 89.47%。我们的研究表明,轻量级 CNN 架构在临床应用中具有潜力,为 ICU 环境下资源受限的实时 AHE 预测提供了有前途的解决方案,从而在改善患者护理方面迈出了重要的一步。

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