Heikkinen L, Harjula A, Mattila S
Ann Chir Gynaecol. 1985;74(3):118-23.
Fifty consecutive coronary artery bypass grafting (Group I) and 50 single valve replacement (Group II) procedures were compared with 50 coronary artery bypass grafting with valve replacement (Group III) procedures and 50 multi-valve procedures (Group IV) to determine the frequency of neurological complications after cardiopulmonary bypass (CPB). The possible risks and aetiological implications were studied. The overall surgical mortality rate was 7.5%, being 0%, 4%, 6% and 20%, respectively for the different groups. The neurological event was not the primary cause of death in any of the patients. After CPB, neurological manifestations occurred in 4% of the patients in Gr. I, in 6% in Gr. II, in 4% in Gr. III, and in 8% in Gr. IV. Three patients had peripheral nerve paresis. The age of the patients and the duration of the CPB operation were not factors in the risk of neurological complications. Previous neurological events seemed to increase the frequency of postoperative neurological disorders, whereas combined procedures were no more dangerous in this respect.
将50例连续冠状动脉搭桥手术（第一组）和50例单瓣膜置换手术（第二组）与50例冠状动脉搭桥联合瓣膜置换手术（第三组）和50例多瓣膜手术（第四组）进行比较，以确定体外循环（CPB）后神经系统并发症的发生率。研究了可能的风险及病因学影响。总体手术死亡率为7.5%，不同组分别为0%、4%、6%和20%。神经系统事件并非任何患者的主要死亡原因。CPB后，第一组4%的患者出现神经系统表现，第二组为6%，第三组为4%，第四组为8%。3例患者出现周围神经麻痹。患者年龄和CPB手术持续时间并非神经系统并发症风险的影响因素。既往神经系统事件似乎会增加术后神经系统疾病的发生率，而联合手术在这方面并无更大风险。
