Owodunni Oluwafemi P, Biala Eduardo, Sirisegaram Luxey, Bettick Dianne, Gearhart Susan L, Ehrlich April L
Johns Hopkins University School of Medicine, Department of Surgery, Baltimore, MD.
University of New Mexico School of Medicine, Emergency Medicine Albuquerque, NM, US.
Perioper Care Oper Room Manag. 2024 Jun;35. doi: 10.1016/j.pcorm.2024.100383. Epub 2024 Mar 14.
Frailty is common in geriatric emergency surgery and associated with increased risk for poor postoperative outcomes. Frailty screening is challenging in emergency settings. The Edmonton Frail Scale (EFS) is a valid tool to screen for patients at high risk for poor postoperative outcomes. Recently, the EFS was modified to decrease dependence on staff to perform physical measures. This modification, the EFS-Acute Care (EFS-AC), has not been validated. We wish to assess the agreement between the EFS and the EFS-AC.
We performed a prospective cohort study from 10/2021 - 10/2022 screening 688 patients ≥ 65 years with both the EFS and EFS-AC preoperatively. We assessed the ability of the EFS-AC to discriminate frailty identified by the EFS and compared the association of both scales with loss of independence (LOI), hospital length of stay (LOS), ICU admissions, and ICU LOS. Receiver Operator Curves were used to estimate the discriminatory thresholds for LOI.
688 patients with a median age 73 (IQR 68, 77) were enrolled. The EFS-AC was able to discriminate individuals' frailty status by the EFS with excellent agreement (AUC 0.971 [0.958, 0.983]). An EFS-AC threshold score of ≥ 6 points lead to 93.60% of individuals being correctly identified (77.87% sensitivity and 97.00% specificity). Both EFS and EFS-AC ≥ 6 were similarly associated with a higher risk for all clinical outcomes assessed and demonstrated similar ability to predict LOI.
The EFS-AC is a valid preoperative frailty screen, and due to its self-reported nature, can be administered in the acute care setting, during virtual visits, or through digital health apps. Real-time screening can assist with better understanding patient needs and lead to interventions to prevent poor hospital outcomes.
衰弱在老年急诊手术中很常见,且与术后不良结局风险增加相关。在急诊环境中进行衰弱筛查具有挑战性。埃德蒙顿衰弱量表(EFS)是一种用于筛查术后不良结局高风险患者的有效工具。最近,EFS进行了修改,以减少对工作人员进行身体测量的依赖。这种修改后的量表,即急性护理版埃德蒙顿衰弱量表(EFS-AC),尚未得到验证。我们希望评估EFS与EFS-AC之间的一致性。
我们于2021年10月至2022年10月进行了一项前瞻性队列研究,术前使用EFS和EFS-AC对688名年龄≥65岁的患者进行筛查。我们评估了EFS-AC识别EFS所确定的衰弱的能力,并比较了两种量表与独立性丧失(LOI)、住院时间(LOS)、入住重症监护病房(ICU)情况及ICU住院时间的相关性。使用受试者工作特征曲线来估计LOI的鉴别阈值。
共纳入688例患者,中位年龄73岁(四分位间距68, 77)。EFS-AC能够很好地鉴别EFS所确定的个体衰弱状态(曲线下面积0.971 [0.958, 0.983])。EFS-AC阈值评分≥6分可正确识别93.60%的个体(灵敏度77.87%,特异度97.00%)。EFS和EFS-AC评分≥6分均与所有评估的临床结局较高风险相似相关,并显示出相似的预测LOI的能力。
EFS-AC是一种有效的术前衰弱筛查工具,由于其自我报告的性质,可在急性护理环境中、虚拟就诊期间或通过数字健康应用程序进行使用。实时筛查有助于更好地了解患者需求,并促使采取干预措施以预防不良的医院结局。