From the Departments of Medicine.
Anesthesiology and Critical Care Medicine.
Anesth Analg. 2020 Jun;130(6):1493-1503. doi: 10.1213/ANE.0000000000004735.
Perioperative management of older adults is a complex field that is heavily influenced by the clinical heterogeneity of older adults. Frailty-a geriatric syndrome in which a patient is more vulnerable to stressors due to decreases in physical function and reserve-has been indicative of adverse postoperative outcomes. Many tools have been developed to measure frailty that incorporate a variety of factors including physical and cognitive function, comorbidities, self-reported measures of health, and clinical judgment. Most of these frailty assessment tools are able to identify a subset of patients at risk of adverse outcomes including postoperative complications, longer hospital length of stay, discharge to a higher level of care, and mortality. Frailty assessment before surgical interventions can also guide discussions among patients, their families, anesthesiologists, and surgeons to tailor operative plans for patients to mitigate this increased risk. Studies are ongoing to identify interventions in frail patients that can improve postoperative outcomes, but high-quality data in the form of randomized controlled trials are lacking at this time.
老年人围手术期管理是一个复杂的领域,深受老年人临床异质性的影响。衰弱是一种老年综合征,由于身体功能和储备能力下降,患者更容易受到压力源的影响。已经开发出许多工具来衡量衰弱,这些工具结合了多种因素,包括身体和认知功能、合并症、自我报告的健康状况和临床判断。这些衰弱评估工具中的大多数都能够识别出一组有发生不良后果风险的患者,包括术后并发症、住院时间延长、出院到更高水平的护理和死亡。手术干预前的衰弱评估还可以指导患者、家属、麻醉师和外科医生之间的讨论,为患者量身定制手术计划,以降低这种风险增加的风险。目前正在进行研究,以确定可以改善术后结果的虚弱患者的干预措施,但此时缺乏高质量的随机对照试验数据。