Haberal Mehmet
From the Department of General Surgery, Division of Transplantation and Burns, Baskent University, Ankara, Turkey.
Exp Clin Transplant. 2024 Apr;22(Suppl 4):1-6. doi: 10.6002/ect.BDCDSymp.L1.
Tissue and organ transplantation is the best treatment option for end-stage organ failure. However, organ shortage still remains to be the greatest challenge facing the field of organ transplantation. Millions of people die and are buried with healthy organs, which could save the lives of many patients who continue to wait on transplant lists. Countries must aim to work towards a system of matching organs as much as possible with the deceased donation to meet the growing demand for organs. This action will not only result in the reduction of organ trafficking activities but shall also make an enormous difference to those patients awaiting transplants where living organ donors are not an option. Donation after circulator death (DCD) has gained much attention over the last decade as one of the accepted practices in order to expand the donor pool. DCD donation takes place after declaration of death using cardio-respiratory criteria in contrast to donation after brain death (DBD) where neurological criteria are used. Although DCD remains a focus of interest and contributes to donor numbers in many countries, it also poses many challenges medically, ethically and legally.
组织和器官移植是终末期器官衰竭的最佳治疗选择。然而,器官短缺仍然是器官移植领域面临的最大挑战。数以百万计的人去世时,健康的器官随之被埋葬,而这些器官本可以挽救众多仍在移植等候名单上的患者的生命。各国必须致力于建立一个尽可能将器官与死者捐赠相匹配的系统,以满足对器官日益增长的需求。这一行动不仅将减少器官贩运活动,而且对于那些没有活体器官捐赠选择而等待移植的患者来说,也将产生巨大影响。在过去十年中,作为扩大供体库的一种公认做法,心脏死亡后捐赠(DCD)受到了广泛关注。与使用神经学标准的脑死亡后捐赠(DBD)不同,DCD捐赠是在使用心肺标准宣布死亡后进行的。尽管DCD仍然是一个备受关注的焦点,并在许多国家增加了供体数量,但它在医学、伦理和法律方面也带来了许多挑战。