Sydney Urodynamic Centres, Penrith, NSW, Australia.
Western Sydney University, Liverpool, NSW, Australia.
Ultrasound Obstet Gynecol. 2024 Aug;64(2):253-258. doi: 10.1002/uog.27706. Epub 2024 Jul 3.
To determine whether height, weight and body mass index (BMI) are associated with the levator-urethra gap (LUG) measurement, and whether these factors confound the relationship between LUG and symptoms and signs of pelvic organ prolapse (POP).
This was a retrospective study of women seen at a tertiary urogynecology unit between January 2020 and December 2021. Postprocessing of saved ultrasound volume data was used to measure the LUG, blinded against all other data. This measurement was tested for its association with organ descent and hiatal area, and height, weight and BMI were investigated for any potential confounding effect.
The 624 women seen during the inclusion period presented mostly with stress urinary incontinence (448/624 (72%)), urgency urinary incontinence (469/624 (75%)) and/or prolapse (338/624 (54%)). Mean age at assessment was 58 (range, 20-94) years, mean height was 163 (range, 142-182) cm, mean weight was 80 (range, 41-153) kg and mean BMI was 30 (range, 17-65) kg/m. LUG measurements could be obtained in 613 women, resulting in 7356 (12 × 613) measurements. The average LUG in individual women measured 2.35 cm on the right and 2.32 cm on the left side (difference not significant), with a mean ± SD of 2.34 ± 0.63 cm overall. Mean LUG was associated with symptoms and signs of prolapse, both on clinical examination (POP quantification system) and on imaging, but not with height (P = 0.36), weight (P = 0.20) or BMI (P = 0.09).
Levator-urethra gap measurements do not seem to be significantly associated with height, weight or BMI in our population, obviating the need for individualization of LUG. However, this does not exclude interethnic variability of this biometric measure. © 2024 International Society of Ultrasound in Obstetrics and Gynecology.
确定身高、体重和体重指数（BMI）是否与尿道悬带间隙（LUG）测量值相关，以及这些因素是否会混淆 LUG 与盆腔器官脱垂（POP）症状和体征之间的关系。
这是一项回顾性研究，纳入 2020 年 1 月至 2021 年 12 月期间在一家三级妇科泌尿科就诊的女性。使用保存的超声体积数据的后处理来测量 LUG，测量过程对所有其他数据均设盲。该测量值与器官下降和疝囊面积进行了关联测试，并研究了身高、体重和 BMI 是否存在潜在的混杂影响。
在纳入期间就诊的 624 名女性主要表现为压力性尿失禁（448/624 [72%]）、急迫性尿失禁（469/624 [75%]）和/或脱垂（338/624 [54%]）。评估时的平均年龄为 58 岁（范围，20-94 岁），平均身高为 163cm（范围，142-182cm），平均体重为 80kg（范围，41-153kg），平均 BMI 为 30kg/m²（范围，17-65kg/m²）。可在 613 名女性中获得 LUG 测量值，共获得 7356（12×613）个测量值。每位女性的平均 LUG 右侧为 2.35cm，左侧为 2.32cm（差异无统计学意义），总体平均值±标准差为 2.34±0.63cm。平均 LUG 与脱垂的症状和体征相关，包括临床检查（POP 量化系统）和影像学检查，但与身高（P=0.36）、体重（P=0.20）或 BMI（P=0.09）无关。
在我们的人群中，LUG 测量值似乎与身高、体重或 BMI 无明显关联，无需个体化 LUG。然而，这并不能排除这种生物测量指标在不同种族之间的差异。
