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Use of Natural Language Understanding to Facilitate Surgical De-Escalation of Axillary Staging in Patients With Breast Cancer.

作者信息

Carleton Neil, Saadawi Gilan, McAuliffe Priscilla F, Soran Atilla, Oesterreich Steffi, Lee Adrian V, Diego Emilia J

机构信息

Women's Cancer Research Center, UPMC Hillman Cancer Center, Pittsburgh, PA.

Magee Women's Research Institute, Pittsburgh, PA.

出版信息

JCO Clin Cancer Inform. 2024 May;8:e2300177. doi: 10.1200/CCI.23.00177.


DOI:10.1200/CCI.23.00177
PMID:38776506
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11180980/
Abstract

PURPOSE: Natural language understanding (NLU) may be particularly well equipped for enhanced data capture from the electronic health record given its examination of both content-driven and context-driven extraction. METHODS: We developed and applied a NLU model to examine rates of pathological node positivity (pN+) and rates of lymphedema to determine whether omission of routine axillary staging could be extended to younger patients with estrogen receptor-positive (ER+)/cN0 disease. RESULTS: We found that rates of pN+ and arm lymphedema were similar between patients age 55-69 years and ≥70 years, with rates of lymphedema exceeding rates of pN+ for clinical stage T1c and smaller disease. CONCLUSION: Data from our NLU model suggest that omission of sentinel lymph node biopsy might be extended beyond Choosing Wisely recommendations, limited to those older than 70 years and to all postmenopausal women with early-stage ER+/cN0 disease. These data support the recently reported SOUND trial results and provide additional granularity to facilitate surgical de-escalation.

摘要

相似文献

[1]
Use of Natural Language Understanding to Facilitate Surgical De-Escalation of Axillary Staging in Patients With Breast Cancer.

JCO Clin Cancer Inform. 2024-5

[2]
Use of natural language understanding to facilitate surgical de-escalation of axillary staging in patients with breast cancer.

medRxiv. 2024-2-6

[3]
[Optimal treatment of the axilla after positive sentinel lymph node biopsy in early invasive breast cancer. Early results of the OTOASOR trial].

Orv Hetil. 2013-12-8

[4]
Can Genomic Testing Help Refine Choosing Wisely the Omission of Axillary Staging in cN0 Breast Cancer?

J Surg Res. 2024-9

[5]
Axillary reverse mapping: mapping and preserving arm lymphatics may be important in preventing lymphedema during sentinel lymph node biopsy.

J Am Coll Surg. 2008-5

[6]
Omitting axillary staging in selected patients: Rationale of Choosing Wisely in breast cancer treatment.

Surgery. 2023-8

[7]
A patient- and assessor-blinded randomized controlled trial of axillary reverse mapping (ARM) in patients with early breast cancer.

Eur J Surg Oncol. 2019-8-5

[8]
Axillary reverse mapping in breast cancer: a new microsurgical lymphatic-venous procedure in the prevention of arm lymphedema.

Ann Surg Oncol. 2008-11

[9]
Evaluation of the metastatic status of lymph nodes identified using axillary reverse mapping in breast cancer patients.

World J Surg Oncol. 2012-11-1

[10]
[Management of the axilla in breast cancer: evidences and unresolved issues].

Orv Hetil. 2001-9-9

本文引用的文献

[1]
Sentinel Lymph Node Biopsy vs No Axillary Surgery in Patients With Small Breast Cancer and Negative Results on Ultrasonography of Axillary Lymph Nodes: The SOUND Randomized Clinical Trial.

JAMA Oncol. 2023-11-1

[2]
Surgical Management of the Axilla for Breast Cancer.

Hematol Oncol Clin North Am. 2023-2

[3]
Axillary Staging Is Not Justified in Postmenopausal Clinically Node-Negative Women Based on Nodal Disease Burden.

Ann Surg Oncol. 2023-1

[4]
How Often Do Sentinel Lymph Node Biopsy Results Affect Adjuvant Therapy Decisions Among Postmenopausal Women with Early-Stage HR/HER2 Breast Cancer in the Post-RxPONDER Era?

Ann Surg Oncol. 2022-10

[5]
Prevalence of Pathologic N2/N3 Disease in Postmenopausal Women with Clinical N0 ER+/HER2- Breast Cancer.

Ann Surg Oncol. 2022-11

[6]
Impact of RxPONDER and monarchE on the Surgical Management of the Axilla in Patients With Breast Cancer.

J Clin Oncol. 2022-10-10

[7]
De-escalation in breast cancer surgery.

NPJ Breast Cancer. 2022-2-23

[8]
Machine learning in medicine: a practical introduction to natural language processing.

BMC Med Res Methodol. 2021-7-31

[9]
Outcomes After Sentinel Lymph Node Biopsy and Radiotherapy in Older Women With Early-Stage, Estrogen Receptor-Positive Breast Cancer.

JAMA Netw Open. 2021-4-1

[10]
Variations in Persistent Use of Low-Value Breast Cancer Surgery.

JAMA Surg. 2021-4-1

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