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Fertility-preserving myeloablative conditioning using single-dose CD117 antibody-drug conjugate in a rhesus gene therapy model.利用单次剂量 CD117 抗体药物偶联物在恒河猴基因治疗模型中进行生育力保存的清髓预处理。
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Mobilization-based chemotherapy-free engraftment of gene-edited human hematopoietic stem cells.基于动员的基因编辑人造血干细胞无化疗植入。
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Design and Synthesis of Tesirine, a Clinical Antibody-Drug Conjugate Pyrrolobenzodiazepine Dimer Payload.临床抗体药物偶联物吡咯并苯二氮䓬二聚体有效载荷替西瑞林的设计与合成。
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(211)Astatine-Conjugated Monoclonal CD45 Antibody-Based Nonmyeloablative Conditioning for Stem Cell Gene Therapy.基于砹标记的单克隆CD45抗体的非清髓性预处理用于干细胞基因治疗
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7
Radioimmunotherapy-based conditioning for hematopoietic cell transplantation in children with malignant and nonmalignant diseases.基于放射性免疫疗法的条件预处理用于儿童恶性和非恶性疾病的造血细胞移植。
Blood. 2011 Apr 28;117(17):4642-50. doi: 10.1182/blood-2010-06-284349. Epub 2011 Feb 15.
8
Haemopoietic stem-cell transplantation with antibody-based minimal-intensity conditioning: a phase 1/2 study.基于抗体的低强度预处理的造血干细胞移植:一项1/2期研究。
Lancet. 2009 Sep 12;374(9693):912-20. doi: 10.1016/S0140-6736(09)60945-4. Epub 2009 Sep 2.

A new step toward non-genotoxic conditioning prior to hematopoietic stem cell transplantation.

作者信息

Cavazzana Marina, Calvo Charlotte

机构信息

Université Paris Cité, Paris, France; Département de Biothérapie Hospital Necker-Enfants Malades, Assistance Publique-Hôpitaux de Paris, Paris, France; Centre d'Investigation Clinique en Biothérapie, INSERM UMR1163, Paris, France; Imagine Institute, Paris, France.

Université Paris Cité, Paris, France; Department of Paediatric Immunology and Haematology, Robert Debré Hospital, Assistance Publique-Hôpitaux de Paris, Paris, France; Institut de Recherche Saint-Louis, INSERM U976, Paris, France.

出版信息

Mol Ther. 2024 Jun 5;32(6):1604-1605. doi: 10.1016/j.ymthe.2024.05.025. Epub 2024 May 21.

DOI:10.1016/j.ymthe.2024.05.025
PMID:38776908
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11184374/
Abstract
摘要