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[用铊-201发射计算机断层扫描评估心肌梗死中的心肌存活情况]

[Evaluation of myocardial viability in myocardial infarction by thallium-201 emission computed tomography].

作者信息

Tamaki N, Kodama S, Yonekura Y, Mukai T, Torizuka K, Tamaki S, Nohara R, Suzuki Y, Kambara H, Kawai C

出版信息

J Cardiogr. 1985 Mar;15(1):1-11.

PMID:3877772
Abstract

Stress thallium-201 emission computed tomography (ECT) was performed for 24 patients with myocardial infarction for quantitative evaluation of regional thallium redistribution and washout. ECT was performed using a rotating gamma camera 10 minutes and 2.5 hours after thallium injection during maximal exercise. Three short-axis sections and one central long-axis section were selected for the circumferential profile curves. Redistribution (%) and washout (%) were calculated from the stress and redistribution profile curves in each section. These parameters were evaluated by comparison with regional wall motion on radiographic contrast ventriculography. Forty-eight of the 52 segments (92%) with normal thallium uptake showed normal wall motion. Among the segments with abnormal thallium uptake, normal or hypokinetic wall motion was observed in 12 of 13 segments (92%) with more than 20% redistribution and in 16 of 19 segments (84%) with 10-20% redistribution, while it was observed in only 15 of 36 segments (42%) without redistribution (p less than 0.001). Among 48 infarcted segments, 16 segments (33%) showed significant redistribution on ECT analysis. Normal or hypokinetic wall motion was observed in three of five segments (60%) with more than 20% redistribution, and in 10 of 11 segments (91%) with 10-20% redistribution, while it was seen in only eight of 30 segments (17%) without redistribution (p less than 0.005).

摘要

对24例心肌梗死患者进行了负荷铊-201发射计算机断层扫描(ECT),以定量评估局部铊再分布和洗脱情况。在最大运动期间铊注射后10分钟和2.5小时,使用旋转γ相机进行ECT检查。选择三个短轴切面和一个中央长轴切面绘制圆周轮廓曲线。根据每个切面的负荷和再分布轮廓曲线计算再分布率(%)和洗脱率(%)。通过与放射造影心室造影的局部室壁运动进行比较来评估这些参数。52个铊摄取正常的节段中有48个(92%)室壁运动正常。在铊摄取异常的节段中,13个再分布超过20%的节段中有12个(92%)、19个再分布为10%-20%的节段中有16个(84%)观察到正常或运动减弱的室壁运动,而在36个无再分布的节段中只有15个(42%)观察到这种情况(p<0.001)。在48个梗死节段中,16个节段(33%)在ECT分析中显示有明显再分布。5个再分布超过20%的节段中有3个(60%)、11个再分布为10%-20%的节段中有10个(91%)观察到正常或运动减弱的室壁运动,而在30个无再分布的节段中只有8个(17%)观察到这种情况(p<0.005)。

相似文献

1
[Evaluation of myocardial viability in myocardial infarction by thallium-201 emission computed tomography].[用铊-201发射计算机断层扫描评估心肌梗死中的心肌存活情况]
J Cardiogr. 1985 Mar;15(1):1-11.
2
[Cardiac inotropic reserve examined by postextrasystolic potentiation and redistribution of exercise thallium-201 scintigraphy].[通过早搏后增强及运动铊-201闪烁显像再分布检测心脏变力性储备]
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Relationship between reverse redistribution on planar thallium scintigraphy and regional myocardial viability: a correlative PET study.平面铊闪烁显像上的反向再分布与局部心肌存活能力的关系:一项相关的正电子发射断层显像(PET)研究
J Nucl Med. 1995 Feb;36(2):180-7.
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Regional uptake of [123I]-16-iodo3-R,S-methyl hexadecanoic acid in patients with myocardial infarction. Comparison with thallium 201 uptake and wall motion.心肌梗死患者对[123I]-16-碘-3-R,S-甲基十六烷酸的局部摄取。与铊201摄取及室壁运动的比较。
Am J Card Imaging. 1994 Jan;8(1):1-7.
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[Quantitative correlation between thallium-201 myocardial emission computed tomography and left ventriculography in old myocardial infarction].
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[Clinical value of thallium-201 reinjection after delayed imaging in patient showing incomplete or no redistribution].
Nihon Igaku Hoshasen Gakkai Zasshi. 1991 May 25;51(5):567-73.
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[Stress thallium-201 myocardial emission CT: comparative evaluation with coronary arteriography and left ventriculography].[应激铊-201心肌发射型计算机断层扫描:与冠状动脉造影和左心室造影的对比评估]
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