Zhang Teng, Cao Rui, Li Jingying, Tang Hanxiao, Su Hang, Feng Weisheng, Zhang Zhijuan
College of Pharmacy, Henan University of Chinese Medicine, Jinshui East Road 156, Zhengzhou, 450046, China.
College of Chinese Medical Sciences, Henan University of Chinese Medicine, Zhengzhou, 450046, China.
Sci Rep. 2024 May 23;14(1):11740. doi: 10.1038/s41598-024-62177-x.
Based on the dual response of RhB@UiO-67 (1:6) to Cu and Fe, a proportional fluorescent probe with (I/I) as the output signal was developed to recognize Cu and Fe. Developing highly sensitive and selective trace metal ions probes is crucial to human health and ecological sustainability. In this work, a series of ratio fluorescent probes (RhB@UiO-67) were successfully synthesized using a one-pot method to enable fluorescence sensing of Cu and Fe at low concentrations. The proportional fluorescent probe RhB@UiO-67 (1:6) exhibited simultaneous quenching of Cu and Fe, which was found to be of interest. Furthermore, the limits of detection (LODs) for Cu and Fe were determined to be 2.76 μM and 0.76 μM, respectively, for RhB@UiO-67 (1:6). These values were significantly superior to those reported for previous sensors, indicating the probe's effectiveness in detecting Cu and Fe in an ethanol medium. Additionally, RhB@UiO-67 (1:6) demonstrated exceptional immunity and reproducibility towards Cu and Fe. The observed fluorescence quenching of Cu and Fe was primarily attributed to the mechanisms of fluorescence resonance energy transfer (FRET), photoinduced electron transfer (PET), and competitive absorption (CA). This work establishes a valuable foundation for the future study and utilization of Cu and Fe sensing technologies.
基于RhB@UiO - 67（1:6）对铜和铁的双重响应，开发了一种以（I/I）为输出信号的比例荧光探针来识别铜和铁。开发高灵敏度和高选择性的痕量金属离子探针对于人类健康和生态可持续性至关重要。在这项工作中，采用一锅法成功合成了一系列比例荧光探针（RhB@UiO - 67），以实现对低浓度铜和铁的荧光传感。比例荧光探针RhB@UiO - 67（1:6）对铜和铁同时表现出猝灭作用，这一现象值得关注。此外，对于RhB@UiO - 67（1:6），铜和铁的检测限分别确定为2.76 μM和0.76 μM。这些值明显优于先前报道的传感器的值，表明该探针在乙醇介质中检测铜和铁的有效性。此外，RhB@UiO - 67（1:6）对铜和铁表现出优异的抗干扰性和重现性。观察到的铜和铁的荧光猝灭主要归因于荧光共振能量转移（FRET）、光致电子转移（PET）和竞争吸收（CA）机制。这项工作为未来铜和铁传感技术的研究和应用奠定了有价值的基础。
