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Allogeneic hematopoietic cell transplantation with sequential conditioning regimen in relapsed refractory acute myeloid leukemia.

作者信息

Tolosa-Ridao Carles, Suárez-Lledó María, Jiménez-Vicente Carlos, Cortés-Bullich Albert, Merchan Beatriz, Martínez-Roca Alexandra, Guijarro Francisca, Castaño-Díez Sandra, Rosiñol Laura, Fernández-Avilés Francesc, Martínez Carmen, Díaz-Beya Marina, Esteve Jordi, Rovira Montserrat, Salas María Queralt

机构信息

Hematology Department, Hospital Universitari Mútua Terrassa, Barcelona, Spain.

Hematopoietic Transplantation Unit, Hematology Department, Clinical Institute of Hematology and Oncology (ICMHO), Hospital Clínic de Barcelona, Barcelona, Spain.

出版信息

Bone Marrow Transplant. 2024 Aug;59(8):1199-1201. doi: 10.1038/s41409-024-02310-6. Epub 2024 May 22.

DOI:10.1038/s41409-024-02310-6
PMID:38778147
Abstract
摘要

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Allogeneic hematopoietic cell transplantation with sequential conditioning regimen in relapsed refractory acute myeloid leukemia.采用序贯预处理方案的异基因造血细胞移植治疗复发难治性急性髓系白血病。
Bone Marrow Transplant. 2024 Aug;59(8):1199-1201. doi: 10.1038/s41409-024-02310-6. Epub 2024 May 22.
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[Clinical outcome of allogeneic hematopoietic stem cell transplantation with FLAG sequential busulfan/cyclophosphamide conditioning regimen for refractory/relapsed acute myeloid leukemia].[采用FLAG序贯白消安/环磷酰胺预处理方案进行异基因造血干细胞移植治疗难治/复发急性髓系白血病的临床结局]
Zhonghua Nei Ke Za Zhi. 2018 Aug 1;57(8):576-581. doi: 10.3760/cma.j.issn.0578-1426.2018.08.008.
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Similar outcome of allogeneic stem cell transplantation after myeloablative and sequential conditioning regimen in patients with refractory or relapsed acute myeloid leukemia: A study from the Société Francophone de Greffe de Moelle et de Thérapie Cellulaire.异基因造血干细胞移植后清髓性和序贯预处理方案在难治或复发急性髓系白血病患者中的相似结局：来自法国骨髓和细胞治疗协会的一项研究。
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Time-to-Event Ratio to Predict Outcome in Patients with Acute Myeloid Leukemia Undergoing Allogeneic Hematopoietic Cell Transplantation?用于预测接受异基因造血细胞移植的急性髓系白血病患者预后的事件发生时间比？
Biol Blood Marrow Transplant. 2017 Oct;23(10):1804-1808. doi: 10.1016/j.bbmt.2017.06.016. Epub 2017 Jul 5.
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Efficacy and safety of cladribine in combination with busulfan and cyclophosphamide as an intensive conditioning regimen preceding allogeneic hematopoietic stem cell transplantation in relapsed or refractory acute myeloid leukemia.克拉屈滨联合白消安和环磷酰胺作为复发或难治性急性髓系白血病异基因造血干细胞移植前强化预处理方案的疗效和安全性。
Transpl Immunol. 2024 Jun;84:102037. doi: 10.1016/j.trim.2024.102037. Epub 2024 Mar 16.
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Intermediate intensity conditioning regimen containing FLAMSA, treosulfan, cyclophosphamide, and ATG for allogeneic stem cell transplantation in elderly patients with relapsed or high-risk acute myeloid leukemia.氟达拉滨、噻替哌、环磷酰胺和 ATG 组成的中等强度预处理方案用于治疗复发或高危急性髓系白血病老年患者的异基因造血干细胞移植。
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Idarubicin-intensified BUCY2 conditioning regimen improved survival in high-risk acute myeloid, but not lymphocytic leukemia patients undergoing allogeneic hematopoietic stem cell transplantation: A retrospective comparative study.伊达比星强化的BUCY2预处理方案改善了接受异基因造血干细胞移植的高危急性髓系白血病患者的生存率，但对淋巴细胞白血病患者无效：一项回顾性比较研究。
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本文引用的文献

1
Diagnosis and management of AML in adults: 2022 recommendations from an international expert panel on behalf of the ELN.成人 AML 的诊断与治疗：ELN 专家组代表发布的 2022 年国际专家建议
Blood. 2022 Sep 22;140(12):1345-1377. doi: 10.1182/blood.2022016867.
2
Allogeneic Stem Cell Transplantation with Sequential Melphalan-Based Conditioning in AML: Residual Morphological Blast Count Determines the Risk of Relapse.急性髓系白血病中基于美法仑序贯预处理的异基因干细胞移植：残留形态学原始细胞计数决定复发风险
Cancer Manag Res. 2022 Feb 15;14:547-559. doi: 10.2147/CMAR.S339846. eCollection 2022.
3
Evaluation of six different types of sequential conditioning regimens for allogeneic stem cell transplantation in relapsed/refractory acute myelogenous leukemia - a study of the Acute Leukemia Working Party of the EBMT.
复发性/难治性急性髓系白血病异基因干细胞移植六种不同类型序贯预处理方案的评估——欧洲血液与骨髓移植协会急性白血病工作组的一项研究
Leuk Lymphoma. 2021 Feb;62(2):399-409. doi: 10.1080/10428194.2020.1827248. Epub 2020 Oct 11.
4
Sequential treatment with FLAG-IDA/treosulfan conditioning regimen for patients with active acute myeloid leukemia.对于患有活动期急性髓系白血病的患者，采用 FLAG-IDA/依托泊苷预处理方案进行序贯治疗。
Ann Hematol. 2020 Dec;99(12):2939-2945. doi: 10.1007/s00277-020-04232-x. Epub 2020 Sep 6.
5
Sequential therapy for patients with primary refractory acute myeloid leukemia: a historical prospective analysis of the German and Israeli experience.原发性难治性急性髓系白血病患者的序贯治疗：德国和以色列经验的历史性前瞻性分析。
Haematologica. 2019 Sep;104(9):1798-1803. doi: 10.3324/haematol.2018.203869. Epub 2019 Feb 7.
6
Hematopoietic stem-cell transplantation for acute leukemia in relapse or primary induction failure.造血干细胞移植治疗复发或初次诱导失败的急性白血病。
J Clin Oncol. 2010 Aug 10;28(23):3730-8. doi: 10.1200/JCO.2010.28.8852. Epub 2010 Jul 12.
7
Allogeneic stem-cell transplantation in patients with refractory acute leukemia: a long-term follow-up.难治性急性白血病患者的异基因干细胞移植：长期随访
Bone Marrow Transplant. 2006 Jan;37(1):45-50. doi: 10.1038/sj.bmt.1705207.
8
Disease burden may identify patients more likely to benefit from second allogeneic hematopoietic stem cell transplantation to treat relapsed acute myelogenous leukemia.疾病负担可能有助于识别哪些患者更有可能从第二次异基因造血干细胞移植中获益，以治疗复发的急性髓性白血病。
Bone Marrow Transplant. 2005 Jul;36(2):157-62. doi: 10.1038/sj.bmt.1705011.