From the Department of Ophthalmology, UTSW Medical Center, Dallas, Texas (Bakr); Department of Ophthalmology, Cairo University, Cairo, Egypt (Bakr); Department of Ophthalmology, Harvey and Bernice Jones Eye Institute, University of Arkansas for Medical Sciences, Little Rock, Arkansas (Elhusseiny, Toma, Sallam); Department of Ophthalmology, Ain Shams University Hospitals, Cairo, Egypt (Toma, Sallam); Department of Ophthalmology, Gloucestershire Hospitals, Gloucestershire, United Kingdom (Sallam).
J Cataract Refract Surg. 2024 Sep 1;50(9):956-962. doi: 10.1097/j.jcrs.0000000000001493.
To compare the rates of intraoperative complications, cystoid macular edema (CME), and visual outcomes in eyes that underwent combined phacovitrectomy (Phaco-PPV) with those with stand-alone phacoemulsification.
A multicenter database study across 8 ophthalmology departments in the United Kingdom.
Retrospective, nonrandomized, multicenter comparative study.
We extracted data for patients who underwent Phaco-PPV and stand-alone phacoemulsification from January 2000 through May 2015. The primary study outcomes were the rates of intraoperative complications and CME postoperatively.
The study included 2222 eyes in the combined Phaco-PPV group and 112 689 in the stand-alone phacoemulsification group. The combined Phaco-PPV group had a higher incidence of posterior capsule rupture (2.7% vs 1.7%), dropped lens fragments (0.5% vs 0.2%), suprachoroidal hemorrhage (0.4% vs 0.1%), and CME (3.6 vs 1.1%) ( P < .001). The mean preoperative visual acuity (VA) was lower in the combined Phaco-PPV group, with a mean VA of 0.98 vs 0.68 logMAR (Snellen ∼20/200 vs 20/100) in the stand-alone phacoemulsification group ( P < .001). VA at 24 weeks was lower in the combined Phaco-PPV group (mean VA 0.67 vs 0.22 logMAR (Snellen ∼20/100 vs 20/32), P < .001).
Combined Phaco-PPV had higher rates of intraoperative complications and CME, along with a lower postoperative VA, when compared with stand-alone phacoemulsification surgery.
比较行联合 phacovitrectomy（Phaco-PPV）与单纯 phacoemulsification 手术的眼内术中并发症、囊样黄斑水肿（CME）和视力结果的发生率。
在英国 8 个眼科系进行的多中心数据库研究。
回顾性、非随机、多中心比较研究。
我们从 2000 年 1 月至 2015 年 5 月提取接受 Phaco-PPV 和单纯 phacoemulsification 的患者的数据。主要研究结果是术中并发症和术后 CME 的发生率。
联合 Phaco-PPV 组 2222 只眼，单纯 phacoemulsification 组 112689 只眼。联合 Phaco-PPV 组后囊破裂发生率较高（2.7%比 1.7%），晶状体碎片脱落（0.5%比 0.2%），脉络膜上腔出血（0.4%比 0.1%）和 CME（3.6%比 1.1%）（P<0.001）。联合 Phaco-PPV 组术前平均视力（VA）较低，单纯 phacoemulsification 组 VA 平均为 0.98 比 0.68 logMAR（Snellen 约 20/200 比 20/100）（P<0.001）。24 周时联合 Phaco-PPV 组 VA 较低（平均 VA 0.67 比 0.22 logMAR（Snellen 约 20/100 比 20/32），P<0.001）。
与单纯 phacoemulsification 手术相比，联合 Phaco-PPV 术中并发症和 CME 发生率较高，术后 VA 较低。
