基于胶原蛋白的板层角膜移植用人工角膜：早期病例报告。
Collagen-Based Artificial Cornea for Lamellar Keratoplasty: An Early Case Report.
机构信息
Krasnov Research Institute of Eye Diseases, Moscow, Russia.
I.M. Sechenov First Moscow State Medical University, Moscow, Russia.
出版信息
Cornea. 2024 Sep 1;43(9):1181-1183. doi: 10.1097/ICO.0000000000003583. Epub 2024 May 23.
PURPOSE
The aim of this study was to evaluate Viscoll collagen membrane (VCM) for lamellar keratoplasty.
METHODS
A 54-year-old man with grade 4 recurrent pterygium underwent lamellar keratoplasty using VCM as the graft material. Standard keratoplasty postoperative treatments, including topical antibiotic-corticosteroid and artificial tears, were administered.
RESULTS
Complete graft epithelialization was achieved after 4 days of the surgery. Follow-up at 9 months showed no pterygium recurrence as well as good integration of the VCM graft into the surrounding tissues with preserved transparency.
CONCLUSIONS
This case demonstrated that VCM possesses great potential as an alternative to the human donor cornea for lamellar keratoplasty; however, the application of VCM for lamellar keratoplasty still needs additional evaluation.
目的
本研究旨在评估 Viscoll 胶原膜（VCM）在板层角膜移植中的应用。
方法
一名 54 岁男性因 4 级复发性翼状胬肉行板层角膜移植术，采用 VCM 作为移植物材料。术后给予标准的角膜移植后治疗，包括局部抗生素皮质类固醇和人工泪液。
结果
术后 4 天，移植完全上皮化。随访 9 个月，未见翼状胬肉复发，VCM 移植物与周围组织良好融合，保持透明。
结论
本病例表明，VCM 作为板层角膜移植的供体角膜替代物具有很大的潜力；然而，VCM 在板层角膜移植中的应用仍需要进一步评估。
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