喷他脒治疗获得性免疫缺陷综合征中的卡氏肺孢子虫肺炎。与急性肾衰竭和肌红蛋白尿的关联。
Pentamidine treatment of Pneumocystis carinii pneumonia in the acquired immunodeficiency syndrome. Association with acute renal failure and myoglobinuria.
作者信息
Sensakovic J W, Suarez M, Perez G, Johnson E S, Smith L G
出版信息
Arch Intern Med. 1985 Dec;145(12):2247.
PMID:3878136
Abstract
A 31-year-old man with acquired immunodeficiency syndrome and biopsy-proved Pneumocystis carinii pneumonia developed acute renal failure, elevated creatinine kinase levels, and myoglobin in both serum and urine while being treated with pentamidine. The patient was receiving no other nephrotoxic medications at the time, and these unusual complications were directly related to the pentamidine.
摘要
一名31岁患获得性免疫缺陷综合征且经活检证实患有卡氏肺孢子虫肺炎的男子，在接受喷他脒治疗期间出现急性肾衰竭、肌酐激酶水平升高以及血清和尿液中均出现肌红蛋白。该患者当时未服用其他有肾毒性的药物，这些不寻常的并发症与喷他脒直接相关。
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