Lozhkina A N, Aleshkin V A
Biull Eksp Biol Med. 1985 Dec;100(12):694-6.
In vitro experiments have shown that C1q at a concentration of 8-250 mkg/ml produced a 1.5-2-fold increase in platelet adhesion to glass. Low doses (4-60 mkg/ml) enhanced platelet splitting 2-3-fold. C1q did not cause platelet aggregation or change ADP-, adrenalin- and thrombin-induced aggregation. C1q participation in the induction of immune response is suggested.
体外实验表明，浓度为8 - 250微克/毫升的C1q可使血小板对玻璃的黏附增加1.5至2倍。低剂量（4 - 60微克/毫升）可使血小板裂解增强2至3倍。C1q不会引起血小板聚集，也不会改变由二磷酸腺苷、肾上腺素和凝血酶诱导的聚集。提示C1q参与免疫反应的诱导过程。
