Oragui Chika C, Dilibe Arthur
Pediatrics, Pediatric Intensive Care Unit (PICU), Stanford University School of Medicine, Lucile Packard Children's Hospital, Palo Alto, USA.
Internal Medicine, ECU Health, East Carolina University, Greenville, USA.
Cureus. 2024 May 23;16(5):e60927. doi: 10.7759/cureus.60927. eCollection 2024 May.
In 2019, the emergence of the coronavirus disease 2019 (COVID-19) virus triggered a global pandemic, reminiscent of the magnitude witnessed during the flu pandemic of 1918. Initially, children often presented with either asymptomatic or mild upper respiratory tract infection symptoms. However, in the post-acute phase, a distinct syndrome affecting multiple organ systems emerged, sharing similarities with Kawasaki's disease. This syndrome was later classified as multisystem inflammatory syndrome in children (MIS-C) by the Pediatric Intensive Care Society in April 2020. Notably, cardiac manifestations and complications associated with COVID-19 constitute a significant source of morbidity and mortality, characterized by left ventricular dysfunction, cardiac conduction abnormalities, and arrhythmias. Although cases of arrhythmias with MIS-C are rare in the literature, we present a unique case involving a 14-year-old without known cardiac risk factors who presented with conduction abnormalities and fatal arrhythmias secondary to MIS-C.
2019年，2019冠状病毒病（COVID-19）病毒的出现引发了一场全球大流行，让人想起1918年流感大流行时的规模。最初，儿童通常表现为无症状或轻度上呼吸道感染症状。然而，在急性期后，出现了一种影响多个器官系统的独特综合征，与川崎病有相似之处。该综合征后来在2020年4月被儿科重症监护学会归类为儿童多系统炎症综合征（MIS-C）。值得注意的是，与COVID-19相关的心脏表现和并发症是发病和死亡的重要来源，其特征为左心室功能障碍、心脏传导异常和心律失常。尽管文献中MIS-C伴发心律失常的病例很少见，但我们报告了一例独特病例，一名14岁、无已知心脏危险因素的儿童因MIS-C出现传导异常和致命性心律失常。
