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使用双极骨软骨同种异体移植和3D打印治疗感染性创伤后膝关节骨缺损:一例报告

Infected Post-traumatic Bone Defect of the Knee using Bipolar Osteochondral Allograft and 3D Printing: A Case Report.

作者信息

Medina-García Juan Camilo, Rios Adolfo de Los, Benedetti Fernando, Reina-Ramirez Federico, Llano Juan David Urrea, Zuluaga-Botero Mauricio

机构信息

Limb of Lengthening and Reconstruction Unit, Clínica Imbanaco Grupo QuirónSalud, Cali, Colombia.

Department of Surgical Clinics, Faculty of Health Sciences, Pontificia Universidad Javeriana Cali, Colombia.

出版信息

J Orthop Case Rep. 2024 May;14(5):109-114. doi: 10.13107/jocr.2024.v14.i05.4452.

Abstract

INTRODUCTION

Transplantation with fresh cadaveric osteochondral allograft (FOCA) is frequently used in defects of the femoral condyle and tibial plateau to preserve the knee joint. However, the use of FOCA in bipolar lesions remains controversial in cases with bipolar defects and a history of infection.

CASE REPORT

We present a 21-year-old male patient with a massive post-traumatic osteochondral defect of the lateral compartment of the knee and a history of infection, treated by a two-stage approach. In stage 1, infection was eradicated, and joint function recovered with aggressive debridement, polymethyl methacrylate beads, bone cement spacers, and Judet's quadricepsplasty. In stage 2, transplantation was performed with a bipolar FOCA. All treatments were planned using 3D-printed models.

CONCLUSION

The two-stage approach and 3D planning can increase the chances of transplant success by preparing the future allograft bed and obtaining an optimal match between the cadaveric allograft and the patient's defect in cases with potential contraindications, such as a bipolar lesion in the femoral condyle and tibial plateau and a history of infection. A combined approach may lead to a more beneficial outcome for the patient to preserve joint function and improve quality of life.

摘要

引言

新鲜尸体骨软骨异体移植(FOCA)常用于股骨髁和胫骨平台缺损以保留膝关节。然而,在存在双极缺损和感染史的病例中,FOCA用于双极病变仍存在争议。

病例报告

我们介绍了一名21岁男性患者,其膝关节外侧间室存在巨大创伤后骨软骨缺损且有感染史,采用两阶段方法进行治疗。在第一阶段,通过积极清创、聚甲基丙烯酸甲酯珠、骨水泥间隔物和朱代股四头肌成形术根除感染并恢复关节功能。在第二阶段,采用双极FOCA进行移植。所有治疗均使用3D打印模型进行规划。

结论

在存在潜在禁忌证的病例中,如股骨髁和胫骨平台的双极病变及感染史,两阶段方法和3D规划可通过准备未来的异体移植床并使尸体异体移植与患者缺损实现最佳匹配,增加移植成功的机会。联合方法可能会为患者带来更有益的结果,以保留关节功能并改善生活质量。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/cd63/11111241/cdf609b27989/JOCR-14-109-g001.jpg

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