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用于新鲜尸体骨软骨异体移植手术的三维打印手术模板,并通过多变量计算机断层扫描分析进行尺寸验证。

Three-dimensional printed surgical templates for fresh cadaveric osteochondral allograft surgery with dimension verification by multivariate computed tomography analysis.

作者信息

Huotilainen Eero, Salmi Mika, Lindahl Jan

机构信息

School of Engineering, Aalto University, Espoo, Finland.

School of Engineering, Aalto University, Espoo, Finland.

出版信息

Knee. 2019 Aug;26(4):923-932. doi: 10.1016/j.knee.2019.05.007. Epub 2019 Jun 3.

Abstract

BACKGROUND

The fit of the allograft is a particular concern in fresh cadaveric osteochondral allograft (FOCA) surgery. Digital design and fabrication were utilized in conjunction with traditional surgery to enable efficient discovery and reproduction of appropriately dimensioned allograft.

METHODS

A patient with large osteochondral defects in the lateral femoral condyle was to undergo FOCA surgery. A digital virtual operation was performed, based on computed tomography (CT) images of the patient. Polyamide saw templates were manufactured using a selective laser sintering process, and gypsum powder was used to manufacture preoperative and intraoperative medical models with binder jetting process. The design dimensions were verified numerically by determining the intactness of the section surface and allograft volume based on four independent measurements of the initial design, and an automated design optimization strategy was postulated. For the surgery, a lateral longitudinal approach was employed.

RESULTS

The virtual operation allowed an efficient design of the saw templates. Their shape and dimensions were verified with a numerical CT analysis method. The allograft dimensions (medial-lateral/superior-inferior/anterior-posterior) were approximately 40/28.5/24 mm, respectively, with the anterosuperior corner diagonally removed, yielding a section volume of approximately 16.5 cm. These manually chosen dimensions were reminiscent of the corresponding computationally optimized values.

CONCLUSIONS

Use of computer-aided design in virtual operation planning and three-dimensional printing in the fabrication of designed templates allowed for an efficient FOCA procedure and accurate allograft fitting. The numerical optimization method allowed for a semiautomated design process, which could in turn be realized also with surgical navigation or robotic surgery methods.

摘要

背景

在新鲜尸体骨软骨移植(FOCA)手术中,同种异体移植物的适配性是一个特别需要关注的问题。数字设计和制造技术与传统手术相结合,以便能够高效地发现并复制尺寸合适的同种异体移植物。

方法

一名股骨外侧髁存在大的骨软骨缺损的患者拟接受FOCA手术。基于患者的计算机断层扫描(CT)图像进行了数字虚拟手术。使用选择性激光烧结工艺制造了聚酰胺锯模板,并使用粘结剂喷射工艺用石膏粉制造了术前和术中医学模型。通过基于初始设计的四次独立测量确定截面表面的完整性和同种异体移植物体积,对设计尺寸进行了数值验证,并提出了一种自动设计优化策略。对于手术,采用了外侧纵向入路。

结果

虚拟手术实现了锯模板的高效设计。通过数值CT分析方法验证了它们的形状和尺寸。同种异体移植物的尺寸(内侧-外侧/ superior- inferior/ anterior- posterior)分别约为40/28.5/24毫米,前上角对角切除,截面体积约为16.5立方厘米。这些手动选择的尺寸让人联想到相应的计算优化值。

结论

在虚拟手术规划中使用计算机辅助设计以及在设计模板制造中使用三维打印,实现了高效的FOCA手术和精确的同种异体移植物适配。数值优化方法实现了半自动化设计过程,这反过来也可以通过手术导航或机器人手术方法实现。

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