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[农村人群及炎性风湿性疾病患者中的链球菌抗体]

[Streptococcus antibodies in a rural population and in patients with inflammatory rheumatic diseases].

作者信息

Bosmanský K

出版信息

Z Rheumatol. 1985 Sep-Oct;44(5):213-7.

PMID:3878641
Abstract

An account is given of assessed titres of anti-streptolysin O (ASO) and antihyaluronidase (AH) in rheumatic fever, in rheumatic patients of inactive phase and in tonsillitis. The ASO titre was examined in 1739 members of the general public and in 360 patients with chronic rheumatic diseases. The author analyses 6235 examinations of ASO titres and 1210 AH examinations. In rheumatic fever the mean maximum ASO titre was 397 u, while the mean maximum AH titre was 3583 u. In inactive phase rheumatic patients the mean ASO titre was 187 u, the mean AH titre 630 u. The mean ASO titre at the onset of the disease in tonsillitis was 172 u. During the second examination after 3-4 weeks, the mean rise of the ASO titre was 205 u. A increased AH titre above 1280 u was recorded during the first examination in 35.2%, during the second examination in 52.3%. The mean ASO titre in the population group comprising 1739 subjects was 148 u. A titre increased above 200 u was recorded in 20.7%. The mean ASO titre in rheumatoid arthritis was 139 u, in ankylosing spondylitis 199 u, in systemic lupus erythematosus and diffuse scleroderma 128 u. In all groups the ASO and AH levels were inversely proportional to the age of the examined subject. Attention is drawn to the correct evaluation of the assessed antibody titres.

摘要

本文给出了风湿热、非活动期风湿患者及扁桃体炎患者抗链球菌溶血素O(ASO)和抗透明质酸酶(AH)的检测滴度。对1739名普通民众和360名慢性风湿性疾病患者进行了ASO滴度检测。作者分析了6235次ASO滴度检测和1210次AH检测。在风湿热患者中,ASO平均最高滴度为397单位,而AH平均最高滴度为3583单位。在非活动期风湿患者中,ASO平均滴度为187单位,AH平均滴度为630单位。扁桃体炎发病时ASO平均滴度为172单位。在3 - 4周后的第二次检测中,ASO滴度平均升高205单位。第一次检测时,AH滴度高于1280单位的比例为35.2%,第二次检测时为52.3%。在1739名受试者组成的人群组中,ASO平均滴度为148单位。滴度高于200单位的比例为20.7%。类风湿关节炎患者的ASO平均滴度为139单位,强直性脊柱炎患者为199单位,系统性红斑狼疮和弥漫性硬皮病患者为128单位。在所有组中,ASO和AH水平与受检者年龄呈反比。文中提请注意对所测抗体滴度的正确评估。

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引用本文的文献

1
Antistreptolysin O titer in health and disease: levels and significance.健康与疾病状态下的抗链球菌溶血素O滴度:水平及意义
Pediatr Rep. 2012 Jan 2;4(1):e8. doi: 10.4081/pr.2012.e8. Epub 2012 Feb 9.