Chioin R, Razzolini R, Stritoni P, Daliento L, Corbara F, Boffa M, Calvanese A, Centis R, Gallucci V, Dalla-Volta S
Acta Cardiol. 1985;40(5):447-60.
Natural and post-surgical history has been investigated in 410 pts with mitral stenosis and 209 pts with mixed mitral stenosis and regurgitation. They had undergone cardiac catheterization in the years 1968-1980. Hemodynamic data and clinical status (NYHA class) have been statistically analyzed in order to obtain prognostically useful parameters. In mitral stenosis peak pulmonary artery pressure is the most important parameter for natural history, whereas cardiac index is the leading parameter in the operated patients. Commissurotomy has a very low surgical mortality, largely due to the better conditions of the patients undergoing this type of conservative surgery. Results are similar in mixed mitral stenosis and regurgitation. Surgery markedly improves survival in comparable patients. Therefore, intervention seems to be indicated especially in patients with elevated pulmonary artery pressure, because they can get the maximum advantage at a minimal risk.
对410例二尖瓣狭窄患者和209例二尖瓣狭窄合并反流患者的自然病史和术后病史进行了调查。他们在1968年至1980年间接受了心导管检查。对血流动力学数据和临床状况（纽约心脏协会分级）进行了统计分析，以获得具有预后意义的有用参数。在二尖瓣狭窄中，肺动脉压峰值是自然病史中最重要的参数，而心脏指数是手术患者的主要参数。二尖瓣交界切开术的手术死亡率非常低，这主要是因为接受这种保守手术的患者状况较好。二尖瓣狭窄合并反流的结果相似。手术显著提高了类似患者的生存率。因此，特别是对于肺动脉压升高的患者，似乎有必要进行干预，因为他们可以在最小风险下获得最大益处。
