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上颌窦嵴顶提升术后骨移植材料的吸收速率及其影响因素

Resorption Rates of Bone Graft Materials after Crestal Maxillary Sinus Floor Elevation and Its Influencing Factors.

作者信息

Jing Ling, Su Baohui

机构信息

College of Biomedical Engineering, Sichuan University, Chengdu 610065, China.

出版信息

J Funct Biomater. 2024 May 17;15(5):133. doi: 10.3390/jfb15050133.

Abstract

The aim of this study is to analyze the resorption rate of bone graft materials after crestal sinus floor elevation, study its influencing factors, and improve the long-term success rate of implants after crestal maxillary sinus floor elevation. Measurement and analysis were conducted at six postoperative timepoints (0 months, 6 months, 12 months, 18 months, 24 months, and 30 months) using cone beam computed tomography (CBCT) data on 31 patients from the Chenghuaxinguanghua Dental Clinic who underwent crestal maxillary sinus floor elevation, involving 38 graft sites. The materials resorption rates of the bone graft height (BH) and bone graft width (BW) were assessed. BH and BW resorption rates followed the same trend ( = 0.07), with BH and BW resorption rates decreasing with time (r = -0.32, < 0.01; r = -0.18, < 0.01), and were maximal in the 0-6 month interval, with BH and BW resorption rates of 3.42%/mth and 3.03%/mth, respectively. The average monthly BH and BW resorption rates in the 6-12 month interval rapidly decreased to 1.75%/mth and 1.29%/mth, respectively. The monthly BH and BW resorption rates in the 12-30 month intervals stabilized at 1.45%/mth ( > 0.05) and 1.22%/mth ( > 0.05), respectively. The higher the initial bone graft height (BH), the lower the BH resorption rates (r = -0.98, < 0.05), and the BW resorption rate was different for different graft sites ( = 0.01). The resorption rates of bone graft materials implanted through crestal maxillary sinus floor elevation decreased rapidly within the first 12 months post operation and remained stable after 12 months. BH was identified as a significant factor influencing the resorption rates of bone graft materials. These results could suggest dentists should pay attention to the trend of resorption rates over time and carefully manage the initial height of bone grafts and inspire the research of new bone grafting materials for crestal maxillary sinus floor elevation.

摘要

本研究旨在分析上颌窦嵴顶提升术后骨移植材料的吸收速率,研究其影响因素,并提高上颌窦嵴顶提升术后种植体的长期成功率。利用来自成华新光华口腔诊所的31例接受上颌窦嵴顶提升术患者的锥形束计算机断层扫描(CBCT)数据,在六个术后时间点(0个月、6个月、12个月、18个月、24个月和30个月)进行测量和分析,共涉及38个植骨部位。评估了骨移植高度(BH)和骨移植宽度(BW)的材料吸收速率。BH和BW吸收速率遵循相同趋势(=0.07),BH和BW吸收速率随时间降低(r=-0.32,<0.01;r=-0.18,<0.01),且在0 - 6个月间隔内最大,BH和BW吸收速率分别为3.42%/月和3.03%/月。6 - 12个月间隔内BH和BW的平均每月吸收速率迅速降至分别为1.75%/月和1.29%/月。12 - 30个月间隔内BH和BW的每月吸收速率分别稳定在1.45%/月(>0.05)和1.22%/月(>0.05)。初始骨移植高度(BH)越高,BH吸收速率越低(r=-0.98,<0.05),且不同植骨部位的BW吸收速率不同(=0.01)。通过上颌窦嵴顶提升植入的骨移植材料吸收速率在术后前12个月内迅速下降,12个月后保持稳定。BH被确定为影响骨移植材料吸收速率的一个重要因素。这些结果提示牙医应关注吸收速率随时间的变化趋势,谨慎处理骨移植的初始高度,并激发对上颌窦嵴顶提升新骨移植材料的研究。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/76c2/11121861/5305a7a55b06/jfb-15-00133-g001.jpg

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