Spector Reynold
Department of Medicine, Robert Wood Johnson Medical School, New Brunswick, NJ.
Am J Med. 2024 Oct;137(10):925-928. doi: 10.1016/j.amjmed.2024.05.023. Epub 2024 May 22.
Forty percent of Americans are obese and 20% are overweight. Until recently, notwithstanding great efforts to combat this chronic, worsening epidemic, the only therapy that "worked" was surgery. However, recently, a new class of safe drugs (incretins) have been developed that cause obese patients to lose ∼20 to 25% of their body weight. Herein we recount this revolution and its implications.
40%的美国人肥胖,20%超重。直到最近,尽管为对抗这一慢性且日益严重的流行病付出了巨大努力,但唯一“有效的”疗法是手术。然而,最近研发出了一类新型安全药物(肠促胰岛素),能使肥胖患者减轻约20%至25%的体重。在此我们讲述这一变革及其影响。