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妊娠期糖尿病女性的饮食摄入量与口服葡萄糖耐量试验结果

Dietary Intake and Oral Glucose Tolerance Test Results in Women with Gestational Diabetes.

作者信息

das Chagas Lucas Almeida, Torloni Maria Regina, Silva-Neto Luiz Gonzaga Ribeiro, Dualib Patricia Medici, de Sousa Rosângela Maria Lopes, Bittencourt Jalila Andréa Sampaio, Araujo Júnior Edward, Granese Roberta, Mattar Rosiane

机构信息

Department of Obstetrics, Paulista School of Medicine, Federal University of São Paulo (EPM-UNIFESP), São Paulo 04023-062, SP, Brazil.

Evidence Based Health Care, Department of Medicine, Paulista School of Medicine, Federal University of São Paulo (EPM-UNIFESP), São Paulo 04023-900, SP, Brazil.

出版信息

J Clin Med. 2024 May 16;13(10):2948. doi: 10.3390/jcm13102948.

Abstract

Diet is a risk factor for gestational diabetes mellitus (GDM). There are few studies on women's diet and glucose tolerance test (GTT) results during pregnancy. The objective of this study was to evaluate the relationship between one's previous diet and the number of abnormal values on the diagnostic GTT in women with GDM. We hypothesized that there would be an inverse relation between antioxidant micronutrient consumption and the number of abnormal GTT values. This cross-sectional study included 60 women diagnosed with GDM (2-h, 75 g-GTT), divided in two groups as follows: 1 abnormal glucose value and 2-3 abnormal values. Shortly after the diagnosis, participants answered a validated food frequency questionnaire to assess their food consumption in the last 6 months. The Mann-Whitney test was used to compare the dietary intake of the participants in the two groups. The participant characteristics were similar. The median intake of total calories, carbohydrates, lipids, and proteins did not differ significantly between groups. Participants with 1 abnormal GTT value had significantly higher intakes of fiber (11.9 vs. 11.0 g/day = 0.049), vitamin D (40.6 vs. 40.4 mcg/day = 0.049), and vitamin C (180.0 vs. 151.0 mg/day = 0.008) than those with 2-3 abnormal values. Our results suggest a possible association between the consumption of fiber and antioxidant micronutrients and the number of abnormal GTT values.

摘要

饮食是妊娠期糖尿病(GDM)的一个风险因素。关于孕期女性饮食与葡萄糖耐量试验(GTT)结果的研究较少。本研究的目的是评估既往饮食与GDM女性诊断性GTT异常值数量之间的关系。我们假设抗氧化微量营养素的摄入量与GTT异常值数量之间存在负相关。这项横断面研究纳入了60名被诊断为GDM(2小时,75克葡萄糖耐量试验)的女性,分为以下两组:1个血糖异常值组和2 - 3个异常值组。诊断后不久,参与者回答了一份经过验证的食物频率问卷,以评估她们在过去6个月的食物摄入量。采用曼 - 惠特尼检验比较两组参与者的饮食摄入量。参与者的特征相似。两组之间总热量、碳水化合物、脂质和蛋白质的摄入量中位数无显著差异。与有2 - 3个异常值的参与者相比,有1个GTT异常值的参与者膳食纤维摄入量显著更高(11.9对11.0克/天,P = 0.049)、维生素D摄入量显著更高(40.6对40.4微克/天,P = 0.049)、维生素C摄入量显著更高(180.0对151.0毫克/天,P = 0.008)。我们的结果表明膳食纤维和抗氧化微量营养素的摄入与GTT异常值数量之间可能存在关联。

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