Discipline of Oro-Maxillo-Facial Surgery and Implantology, Faculty of Dental Medicine, Iuliu Hatieganu University of Medicine and Pharmacy, 400029 Cluj-Napoca, Romania.
Department of Maxillo-Facial-Surgery, Cluj County Emergency Clinical Hospital, 400029 Cluj-Napoca, Romania.
Medicina (Kaunas). 2024 Apr 25;60(5):708. doi: 10.3390/medicina60050708.
: A magnetic resonance imaging (MRI) scan is part of the diagnostic protocol in pituitary adenoma patients. The goal of the present study is to present and analyse the MRI appearances of the sphenoid sinus (SS) in patients with non-functioning pituitary adenoma (NFPA). : This is a retrospective case-control study conducted between January 2015 and December 2023 in a tertiary referral hospital. Forty NFPA patients were included in the study group, while the control group consisted of 30 age- and gender-matched cases. : The sellar type of SS pneumatization was the most frequently encountered pattern among both groups. The presence of the lateral recess of the SS, mucosal cysts, and sphenoethmoidal cells was similar in both patient groups. The proportion of patients with SS mucosal thickness greater than 3 mm was 42.5% in NFPA group and 3% in the control group, and this difference was statistically significant ( < 0.001). The space between the two optic nerves was significantly larger in the NFPA group as compared to the control group ( < 0.001). : Our study was able to establish a statistically significant association between the presence of NFPA and both the thickening of the SS mucosa and increased space between optic nerves.
磁共振成像（MRI）扫描是垂体腺瘤患者诊断方案的一部分。本研究的目的是展示和分析无功能垂体腺瘤（NFPA）患者蝶窦（SS）的 MRI 表现。
这是一项回顾性病例对照研究，于 2015 年 1 月至 2023 年 12 月在一家三级转诊医院进行。研究组纳入了 40 例 NFPA 患者，对照组包括 30 例年龄和性别匹配的病例。
两组中最常见的蝶窦气化类型是鞍型。两组患者的蝶窦外侧隐窝、黏膜囊肿和蝶筛窦细胞均相似。NFPA 组中 SS 黏膜厚度大于 3 毫米的患者比例为 42.5%，而对照组为 3%，差异具有统计学意义（<0.001）。与对照组相比，NFPA 组视神经之间的空间明显更大（<0.001）。
我们的研究能够确定 NFPA 的存在与 SS 黏膜增厚和视神经之间空间增大之间存在统计学显著关联。
