Chowdhury M N, Jabbar F A, Kambal A M
Trop Geogr Med. 1985 Dec;37(4):328-33.
Vaginal swabs from 2715 consecutive unselected women with vaginal discharge were examined for Gardnerella vaginalis, Candida albicans and Trichomonas vaginalis. Of 2715 women, 2043 had non-specific vaginitis and G. vaginalis was isolated from 269 cases (13.2%). Thirty five of the strains were isolated together with C. albicans, eight with T. vaginalis, six with Bacteroides species and three each with group B Streptococcus and Staphylococcus aureus. Two hundred and sixteen (80%) of the isolates were from females between the age of 20 and 34. All 269 strains hydrolysed hippurate and fermented starch; 161 (60%) were isolated from swabs without clue cells. Although facts suggest that vaginal discharge in most of these cases had been associated with G. vaginalis, a possible aetiological role for other micro-organisms has not been ruled out. However, successful therapy with metronidazole in 80% of those cases suggests that G. vaginalis is one cause of non-specific vaginitis. The prevalence rate of G. vaginalis in 160 randomly selected women without vaginal discharge was 5%.
对2715例连续入选的有阴道分泌物的未选择女性进行阴道拭子检查,以检测阴道加德纳菌、白色念珠菌和阴道毛滴虫。在2715名女性中,2043例患有非特异性阴道炎,从269例(13.2%)中分离出阴道加德纳菌。35株与白色念珠菌一起分离出,8株与阴道毛滴虫一起分离出,6株与拟杆菌属一起分离出,3株分别与B组链球菌和金黄色葡萄球菌一起分离出。216株(80%)分离自年龄在20至34岁之间的女性。所有269株均水解马尿酸盐并发酵淀粉;161株(60%)从无线索细胞的拭子中分离出。尽管事实表明在大多数这些病例中阴道分泌物与阴道加德纳菌有关,但其他微生物的可能病因作用尚未排除。然而,80%的病例用甲硝唑治疗成功表明阴道加德纳菌是非特异性阴道炎的一个病因。在160名随机选择的无阴道分泌物的女性中,阴道加德纳菌的患病率为5%。