Cottier C, Pfisterer M, Burkart F, Burckhardt D, Grädel E
Z Kardiol. 1985 Dec;74(12):679-84.
Age has been identified as an independent risk factor for coronary artery bypass grafting (CABG). We evaluated, therefore, the perioperative phase and long-term prognosis of all patients over the age of 64 (n = 80), who had been operated on for coronary heart disease at the University Hospital of Basel/Switzerland between 1979 and 1983. These elderly subjects were compared to 80 patients, 50 to 60 years old at the time of CABG, who were matched for degree of angina pectoris, coronary artery disease, left ventricular ejection fraction, sex and year of operation (matched-pairs analysis). Evaluation of long-term prognosis was based on regular clinical controls and on a questionnaire, sent to the patients in June 1984. During the perioperative phase 3 patients over 64 died versus 0 in the group of patients 50-60 years old. There were more complications in the older group (perioperative myocardial infarction 10 vs. 4, pulmonary embolism 2 vs. 0, cerebro-vascular insult 4 vs. 0). Three vs. one permanent pacemaker had to be implanted for irreversible AV-block. The difference in hospital stay, 21 vs. 19 days, was not significant. The cumulative survival rate was in both groups 95% after one year and 86 vs. 92% 5 years after CABG (difference not significant), despite the fact that significantly more elderly patients have had myocardial infarction prior to CABG. After an average follow-up of 28 months, 72% vs. 60% were without thoracic pain; 63 vs. 49% considered themselves in a good overall condition.(ABSTRACT TRUNCATED AT 250 WORDS)
年龄已被确定为冠状动脉旁路移植术(CABG)的一个独立危险因素。因此,我们评估了1979年至1983年间在瑞士巴塞尔大学医院接受冠心病手术的所有64岁以上患者(n = 80)的围手术期和长期预后。将这些老年患者与80例在CABG时年龄为50至60岁的患者进行比较,这些患者在心绞痛程度、冠状动脉疾病、左心室射血分数、性别和手术年份方面进行了匹配(配对分析)。长期预后评估基于定期的临床检查以及1984年6月发给患者的一份问卷。在围手术期,64岁以上的患者中有3例死亡,而50 - 60岁患者组中无死亡病例。老年组并发症更多(围手术期心肌梗死分别为10例和4例,肺栓塞分别为2例和0例,脑血管损伤分别为4例和0例)。因不可逆性房室传导阻滞必须植入永久性起搏器的患者分别为3例和1例。住院时间差异为21天和19天,无统计学意义。尽管在CABG之前有心肌梗死的老年患者明显更多,但两组术后1年的累积生存率均为95%,CABG术后5年分别为86%和92%(差异无统计学意义)。平均随访28个月后,无胸痛的患者分别为72%和60%;认为自己总体状况良好的患者分别为63%和49%。(摘要截选至250字)