Department of Neuropsychiatry, Osaka Medical and Pharmaceutical University, 2-7 Daigaku-machi, Takatsuki, Osaka 569-8686, Japan.
Department of Neuropsychiatry, Kansai Medical University, 10-15 Fumizono-cho, Moriguchi, Osaka 570-8507, Japan.
Asian J Psychiatr. 2024 Jul;97:104082. doi: 10.1016/j.ajp.2024.104082. Epub 2024 May 19.
This study registered consecutive cases to elucidate the efficacy of rTMS treatment for depression within the Japanese public health insurance system. Of the 102 patients with depression who received rTMS over the left dorsolateral prefrontal cortex, 44 (43.1 %) patients reached remission and 14 (13.7 %) patients did not reach remission but responded to treatment. No serious adverse events occurred. Low baseline HAMD-17 score was associated with remission after rTMS treatment. Favorable outcomes of rTMS treatment were shown in this cohort within the Japanese public insurance system. Our results provide insights into rTMS treatment for depression in real-world clinical setting.
本研究登记了连续病例，以阐明重复经颅磁刺激(rTMS)治疗在日本公共医疗保险体系下治疗抑郁症的疗效。在接受左侧背外侧前额叶 rTMS 治疗的 102 例抑郁症患者中，44 例（43.1%）达到缓解，14 例（13.7%）未达到缓解但对治疗有反应。未发生严重不良事件。rTMS 治疗后，基线 HAMD-17 评分较低与缓解相关。在日本公共保险体系中，rTMS 治疗有良好的效果。我们的研究结果为 rTMS 治疗真实世界临床环境中的抑郁症提供了新的见解。
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