Harvard Medical School, 25 Shattuck Street, Boston, MA 02115, USA.
Department of Dermatology, Brigham and Women's Hospital, 221 Longwood Avenue, Boston, MA 02115, USA.
Dermatol Clin. 2024 Jul;42(3):399-404. doi: 10.1016/j.det.2024.02.002. Epub 2024 Mar 15.
Phototherapy has utility as a psoriatic therapy, given its relatively high clinical efficacy, low side effect profile, and lower cost compared to newer effective treatments like biologics and small molecules. Phototherapy has shown Psoriasis Area and Severity Index (PASI)-75 and PASI-90 rates comparable to those of biologics and small molecules, with similarly rapid onsets of action, rates of remission, and quality of life scores. Certain patients may particularly benefit from phototherapy, such as those with localized disease or contraindications to systemic immunomodulatory medication. Phototherapy can be more cost-effective than biologics and conveniently administered at home, making it a valuable therapeutic option for the right patient.
光疗作为一种银屑病治疗方法具有一定的作用，因为它的临床疗效较高，副作用较低，与生物制剂和小分子药物等新型有效治疗方法相比，成本更低。光疗在银屑病面积和严重程度指数（PASI）75 和 PASI90 方面的疗效与生物制剂和小分子药物相当，起效迅速，缓解率和生活质量评分也相当。某些患者可能特别受益于光疗，例如那些患有局部疾病或对全身免疫调节药物有禁忌症的患者。光疗比生物制剂更具成本效益，且方便在家中进行，因此对于合适的患者来说，是一种有价值的治疗选择。
