Division of Gastroenterology, Hennepin Healthcare, 701 Park Avenue, Mail Code O1, Minneapolis, MN 55415, USA.
Division of Gastroenterology and Hepatology, University of Colorado Anschutz Medical Campus, 1635 Aurora Court, Mail Stop F 735, Aurora, CO 80045, USA.
Gastrointest Endosc Clin N Am. 2024 Jul;34(3):417-431. doi: 10.1016/j.giec.2024.02.007. Epub 2024 Apr 10.
Per-oral pancreatoscopy (POP) is a pancreas-preserving modality that allows for targeted pancreatic duct interventions, particularly in cases where standard techniques fail. POP specifically has an emerging role in the diagnosis, risk stratification, and disease extent determination of main duct intraductal papillary mucinous neoplasms (IPMNs). It has also been successfully used for laser ablation of IPMNs in poor surgical candidates, lithotripsy for complex stone disease, and laser stricturoplasty. As experience with POP increases beyond select referral center practices, further studies validating POP efficacy with long-term follow-up will help clarify when POP-guided intervention is most beneficial in relation to surgical intervention.
经口胰腺镜检查（POP）是一种保留胰腺的方法，可进行靶向胰腺管介入，特别是在标准技术失败的情况下。POP 特别在主胰管内乳头状黏液性肿瘤（IPMN）的诊断、风险分层和疾病范围确定方面具有新兴作用。它还成功地用于对手术候选人不佳的 IPMN 进行激光消融、治疗复杂结石病的碎石术以及激光狭窄成形术。随着 POP 经验的增加超出了选择的转诊中心实践，进一步的研究通过长期随访来验证 POP 的疗效将有助于阐明何时 POP 引导的介入与手术干预相比最有益。
