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临床风险评分能够对全膝关节置换术后1年的不满意情况进行早期预测。

A clinical risk score enables early prediction of dissatisfaction 1 year after total knee arthroplasty.

作者信息

Strahl André, Delsmann Maximilian M, Simon Alexander, Ries Christian, Rolvien Tim, Beil Frank Timo

机构信息

Department of Trauma and Orthopaedic Surgery, Division of Orthopaedics, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.

出版信息

Knee Surg Sports Traumatol Arthrosc. 2025 Jan;33(1):252-264. doi: 10.1002/ksa.12277. Epub 2024 May 26.

Abstract

PURPOSE

Dissatisfaction after total knee arthroplasty (TKA) is a prevalent and clinically relevant problem that affects approximately 10%-20% of patients. The aim of this study is to identify factors associated with dissatisfaction 1 year after TKA.

METHODS

A total of 236 patients undergoing TKA were included in this prospective cohort study. Demographic data, preoperative clinical parameters (e.g., axial alignment, osteoarthritis severity) and patient-reported outcome measures (PROMs) were collected preoperatively, at 1 month and 1 year after TKA, encompassing the Knee Society Score (KSS) and Knee injury and Osteoarthritis Outcome Score (KOOS). The primary outcome was dissatisfaction 1 year after TKA, defined as ≤20 points on the KSS satisfaction scale. A risk score based on multiple regression and area under the curve (AUC) analyses was calculated to predict dissatisfaction.

RESULTS

One year after TKA, 16% of the patients were dissatisfied. Dissatisfied patients were significantly younger (p = 0.023) and had a higher body mass index (BMI) (p = 0.007). No differences were observed in preoperative objective (p = 0.903) and functional KSS (p = 0.346), pain (p = 0.306), osteoarthritis severity (p = 0.358), axial knee alignment (p = 0.984) or psychological distress (p = 0.138). The likelihood of dissatisfaction at 1 year was 3.0, 4.0, 7.4, 4.3 and 2.8 times higher amongst patients aged <63.5 years, with a BMI > 30.1 kg/m, a KOOS < 50%, a KSS < 42 points and a KSS < 9 points (all at 1 month), respectively. Using these variables, a risk score with a maximum of 7 points was developed, demonstrating a high predictive value for dissatisfaction (AUC: 0.792 [95% confidence interval: 0.700-0.884], p < 0.001).

CONCLUSION

Dissatisfaction 1 year after TKA can be predicted by a weighted risk score that includes patient age, BMI, pain, subjective functionality and unmet expectation 1 month postoperatively. Using the risk score, early detection of dissatisfaction has the potential to enable targeted interventions and improve patients' quality of life.

LEVEL OF EVIDENCE

Level II, Prognostic study.

摘要

目的

全膝关节置换术(TKA)后患者不满意是一个普遍存在且具有临床相关性的问题,约10%-20%的患者受其影响。本研究旨在确定TKA术后1年与患者不满意相关的因素。

方法

本前瞻性队列研究共纳入236例行TKA的患者。收集患者术前、TKA术后1个月及1年的人口统计学数据、术前临床参数(如轴向对线、骨关节炎严重程度)以及患者报告结局指标(PROMs),包括膝关节协会评分(KSS)和膝关节损伤与骨关节炎结局评分(KOOS)。主要结局为TKA术后1年患者不满意,定义为KSS满意度量表得分≤20分。通过多元回归和曲线下面积(AUC)分析计算风险评分,以预测患者不满意情况。

结果

TKA术后1年,16%的患者表示不满意。不满意的患者明显更年轻(p = 0.023)且体重指数(BMI)更高(p = 0.007)。术前客观指标(p = 0.903)、功能KSS(p = 0.346)、疼痛(p = 0.306)、骨关节炎严重程度(p = 0.358)、膝关节轴向对线(p = 0.984)或心理困扰(p = 0.138)方面未观察到差异。年龄<63.5岁、BMI>30.1kg/m²、KOOS<50%、KSS<42分(均在术后1个月)以及KSS<9分的患者术后1年不满意的可能性分别高3.0、4.0、7.4、4.3和2.8倍。利用这些变量,开发了一个最高7分的风险评分,对患者不满意情况显示出较高的预测价值(AUC:0.792[95%置信区间:0.700-0.884],p<0.001)。

结论

TKA术后1年患者是否不满意可通过一个加权风险评分来预测,该评分包括患者年龄、BMI、疼痛、主观功能以及术后1个月未满足的期望。利用该风险评分,早期发现患者不满意情况有可能实现针对性干预并改善患者生活质量。

证据水平

II级,预后研究。

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