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酒精使用障碍作为军事人员创伤后应激障碍与自杀倾向之间关系的调节因素。

Alcohol use disorder as a moderator of the relationship between posttraumatic stress disorder and suicidality among military personnel.

作者信息

Walton Thomas O, Graupensperger Scott, Walker Denise D, Kaysen Debra

机构信息

Department of Psychiatry and Behavioral Sciences, University of Washington, Seattle, Washington, USA.

School of Social Work, University of Washington, Seattle, Washington, USA.

出版信息

Alcohol Clin Exp Res (Hoboken). 2024 Jun;48(6):1096-1106. doi: 10.1111/acer.15313. Epub 2024 May 26.

Abstract

BACKGROUND

Alcohol use disorder (AUD), posttraumatic stress disorder (PTSD), and suicide are substantial public health concerns among military service members, yet the nature of their relationships is not well understood. Here, we tested the hypothesis that AUD moderates the relationship between PTSD symptom severity and suicidal ideation.

METHODS

This secondary analysis uses data collected at baseline for a randomized clinical trial. The sample consists of 160 active-duty service members from three service branches (Army, Air Force, and Navy). All participants met diagnostic criteria for PTSD and were not engaged in evidence-based PTSD treatment at the time of enrollment. Zero-inflated Poisson generalized linear regression models were used to test the associations of PTSD and AUD symptom severity with the presence and severity of suicidal ideation.

RESULTS

Findings suggest that AUD symptom severity moderates (i.e., amplifies) the relationship between PTSD symptoms and severity of suicidal ideation among military personnel with untreated PTSD. Among service members with mild or absent AUD, we found no significant association between PTSD symptoms and the severity of suicidal ideation. However, when AUD severity was average (i.e., sample mean) or high (mean + 1SD), PTSD symptoms were significantly positively associated with the severity of suicidal ideation.

CONCLUSIONS

This study highlights the importance of assessing AUD and PTSD as a part of suicide risk evaluations of veterans. The results also provide strong support for the maintenance and further development in the military health system of treatment programs that simultaneously address AUD and PTSD comorbidity.

摘要

背景

酒精使用障碍(AUD)、创伤后应激障碍(PTSD)和自杀是军事人员面临的重大公共卫生问题,但其关系的本质尚未得到充分理解。在此,我们检验了AUD调节PTSD症状严重程度与自杀意念之间关系的假设。

方法

本二次分析使用了一项随机临床试验基线时收集的数据。样本包括来自三个军种(陆军、空军和海军)的160名现役军人。所有参与者均符合PTSD的诊断标准,且在入组时未接受循证PTSD治疗。采用零膨胀泊松广义线性回归模型来检验PTSD和AUD症状严重程度与自杀意念的存在及严重程度之间的关联。

结果

研究结果表明,AUD症状严重程度调节(即放大)了未接受治疗的PTSD军事人员中PTSD症状与自杀意念严重程度之间的关系。在AUD症状轻微或不存在的军人中,我们发现PTSD症状与自杀意念严重程度之间无显著关联。然而,当AUD严重程度为平均水平(即样本均值)或较高(均值 + 1标准差)时,PTSD症状与自杀意念严重程度显著正相关。

结论

本研究强调了在退伍军人自杀风险评估中评估AUD和PTSD的重要性。研究结果还为军事卫生系统中同时解决AUD和PTSD共病问题的治疗项目的维持和进一步发展提供了有力支持。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/58ac/12091944/7388717526e2/nihms-2081439-f0001.jpg

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Alcohol use and death by suicide: A meta-analysis of 33 studies.饮酒与自杀死亡:33 项研究的荟萃分析。
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