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食品工业中的合成生物学:进展与挑战

Synthetic biology for the food industry: advances and challenges.

作者信息

Chen Ruipeng, Ren Shuyue, Li Shuang, Zhou Huanying, Jia Xuexia, Han Dianpeng, Gao Zhixian

机构信息

Tianjin Key Laboratory of Risk Assessment and Control Technology for Environment and Food Safety, Tianjin Institute of Environmental and Operational Medicine, Tianjin, China.

出版信息

Crit Rev Biotechnol. 2025 Feb;45(1):23-47. doi: 10.1080/07388551.2024.2340530. Epub 2024 May 26.

Abstract

As global environmental pollution increases, climate change worsens, and population growth continues, the challenges of securing a safe, nutritious, and sustainable food supply have become enormous. This has led to new requirements for future food supply methods and functions. The use of synthetic biology technology to create cell factories suitable for food industry production and renewable raw material conversion into: important food components, functional food additives, and nutritional chemicals, represents an important method of solving the problems faced by the food industry. Here, we review the recent progress and applications of synthetic biology in the food industry, including alternatives to: traditional (artificial pigments, meat, starch, and milk), functional (sweeteners, sugar substitutes, nutrients, flavoring agents), and green (green fiber, degradable packing materials, green packaging materials and food traceability) foods. Furthermore, we discuss the future prospects of synthetic biology-based applications in the food industry. Thus, this review may serve as a reference for research on synthetic biology in the: food safety, food nutrition, public health, and health-related fields.

摘要

随着全球环境污染加剧、气候变化恶化以及人口持续增长,确保安全、营养和可持续的食品供应面临的挑战变得巨大。这对未来食品供应方式和功能提出了新要求。利用合成生物学技术创建适用于食品工业生产的细胞工厂,并将可再生原料转化为重要的食品成分、功能性食品添加剂和营养化学品,是解决食品工业面临问题的重要方法。在此,我们综述了合成生物学在食品工业中的最新进展和应用,包括传统食品(人工色素、肉类、淀粉和牛奶)、功能性食品(甜味剂、代糖、营养素、调味剂)和绿色食品(绿色纤维、可降解包装材料、绿色包装材料和食品可追溯性)的替代品。此外,我们还讨论了基于合成生物学的应用在食品工业中的未来前景。因此,本综述可为食品安全、食品营养、公共卫生及健康相关领域的合成生物学研究提供参考。

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