引言：肾上腺素能受体研究简史。
Introduction: A Short History of Adrenoceptor Research.
机构信息
Department of Pharmacology, University Medical Center, Johannes Gutenberg University, Mainz, Germany.
出版信息
Handb Exp Pharmacol. 2024;285:1-12. doi: 10.1007/164_2024_718.
PMID:38797750
Abstract
This chapter provides a short history of adrenoceptor research starting from the initial discovery of adrenaline. It covers the evolving classification of adrenoceptor subtypes, the cloning of these subtypes from multiple species, and factors such as adrenoceptor regulation, inverse agonism and biased agonism. More details on many of these aspects are provided in other chapters of this volume of Handbook of Experimental Pharmacology.
摘要
本章简要介绍了肾上腺素受体研究的历史，从最初对肾上腺素的发现开始。它涵盖了肾上腺素受体亚型的不断发展的分类、这些亚型从多种物种中的克隆，以及肾上腺素受体调节、反向激动剂和偏向激动剂等因素。本手册实验药理学卷的其他章节提供了这些方面的更多详细信息。
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