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小脑刺激后痉挛型脑瘫组的生物工程学变化

Bioengineering changes in spastic cerebral palsy groups following cerebellar stimulation.

作者信息

Davis R, Gray E, Ryan T, Schulman J

出版信息

Appl Neurophysiol. 1985;48(1-6):111-6. doi: 10.1159/000101113.

DOI:10.1159/000101113
PMID:3879788
Abstract

Quantitative bioengineering tests were performed on 30 spastic cerebral palsy (CP) patients who underwent chronic cerebellar stimulation (CCS) using the fully implantable pulse generator (Neurolith 601, 1.1-1.8 microC/cm2/phase). Using respiratory inductive plethysmography to measure 8 patients with paroxysmal and/or ataxic breathing patterns, 5 were shown to revert to normal with 3 others markedly improved within 5 months of CCS. Compliance testing of the ankle was performed on 4 patients who showed improvement in 9 of the 16 tests performed. Motor performance ability was evaluated with 9 comprehensive tests in 17 patients. Following 1-2 weeks of CCS, 52% showed performance increases greater than 10%, increasing to 62% during the first year.

摘要

对30例接受慢性小脑刺激(CCS)的痉挛性脑瘫(CP)患者进行了定量生物工程测试,使用的是完全植入式脉冲发生器(Neurolith 601,1.1 - 1.8微库仑/平方厘米/相位)。使用呼吸感应体积描记法对8例有阵发性和/或共济失调呼吸模式的患者进行测量,结果显示5例在CCS治疗5个月内恢复正常,另外3例有明显改善。对4例患者进行了踝关节顺应性测试,在16项测试中有9项显示有改善。对17例患者进行了9项综合测试以评估运动表现能力。在CCS治疗1 - 2周后,52%的患者表现提高超过10%,在第一年这一比例增至62%。

相似文献

1
Bioengineering changes in spastic cerebral palsy groups following cerebellar stimulation.小脑刺激后痉挛型脑瘫组的生物工程学变化
Appl Neurophysiol. 1985;48(1-6):111-6. doi: 10.1159/000101113.
2
Reduction of intractable seizures using cerebellar stimulation.
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Cerebellar stimulation for spastic cerebral palsy--double-blind quantitative study.
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Cerebellar stimulation for spastic cerebral palsy: preliminary report; on-going double blind study.小脑刺激治疗痉挛型脑瘫:初步报告;正在进行的双盲研究。
Pacing Clin Electrophysiol. 1987 Jan;10(1 Pt 2):226-31. doi: 10.1111/j.1540-8159.1987.tb05953.x.
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