Global Brain Health Institute, San Francisco, CA, USA.
University of California at San Francisco, San Francisco, CA, USA.
J Appl Gerontol. 2024 Dec;43(12):1997-2006. doi: 10.1177/07334648241254362. Epub 2024 May 27.
We examined whether vision impairment (VI) and hearing impairment (HI) and dual sensory impairment (DSI) affect cognitive performance and whether depression mediates that effect. We examined 55,340 participants from the Survey of Health, Aging and Retirement in Europe, which assessed 32,325 participants in 2011 (baseline, Time 1), 2015 (follow-up, Time 2), sociodemographic data and health factors, self-reported VI, HI, and DSI at baseline, depression, and cognitive performance after four years. A multiple mediator model was tested using bootstrapping and resampling. At baseline, 22.9% had VI, 10.2% HI, and 10.4% had DSI. We found a significant negative association between VI (b = -0.023, = .001) and DSI (b = -0.083, = .001) and cognitive performance; both were also associated with depression, which was linked with poor cognition. VI or DSI among older adults are associated with poor cognitive function directly and indirectly by increasing depression symptoms.
我们研究了视力障碍(VI)、听力障碍(HI)和双重感觉障碍(DSI)是否会影响认知表现,以及抑郁是否会影响这种影响。我们研究了来自欧洲健康、老龄化和退休调查的 55340 名参与者,该调查在 2011 年(基线,第 1 时间点)和 2015 年(随访,第 2 时间点)评估了 32325 名参与者,评估了社会人口统计学数据和健康因素、基线时自我报告的 VI、HI 和 DSI、抑郁以及四年后的认知表现。使用 bootstrap 和重采样测试了多重中介模型。在基线时,22.9%的人有 VI,10.2%的人有 HI,10.4%的人有 DSI。我们发现 VI(b=-0.023,p=.001)和 DSI(b=-0.083,p=.001)与认知表现呈显著负相关;两者也与抑郁有关,抑郁与认知能力下降有关。老年人的 VI 或 DSI 直接或间接通过增加抑郁症状与认知功能差有关。