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非卵巢癌病例:一例伴有水肿样变的巨大平滑肌瘤

When it's not ovarian cancer: A case of a massive leiomyoma with hydropic change.

作者信息

Erfani Hadi, Chiang Sarah, Dickinson Shannan, Chi Dennis S, Kim Sarah H

机构信息

Gynecology Service, Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA.

Department of Pathology, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA.

出版信息

Gynecol Oncol Rep. 2024 May 11;53:101415. doi: 10.1016/j.gore.2024.101415. eCollection 2024 Jun.

Abstract

BACKGROUND

Uterine leiomyomas are benign tumors characterized by pelvic pain and abnormal bleeding. Their evolution can lead to degenerative changes, occasionally mimicking malignancies on imaging, presenting diagnostic challenges.

CASE PRESENTATION

A 31-year-old nulliparous woman presented with symptoms of bloating, cramping, and abdominal distension. Imaging suggested an advanced ovarian malignancy, showing a complex adnexal mass and elevated CA-125 levels. During exploratory laparotomy, what was suspected to be ovarian cancer was instead identified as a large uterine mass on pathologic evaluation revealing a benign leiomyoma with extensive hydropic change.

CONCLUSION

This case highlights the diagnostic intricacies associated with large complex adnexal masses and illustrates how benign conditions like leiomyomas with hydropic degeneration can mimic ovarian cancer. This emphasizes the importance of comprehensive preoperative and intraoperative assessments to tailor management and avoid unindicated radical procedures.

摘要

背景

子宫平滑肌瘤是一种以盆腔疼痛和异常出血为特征的良性肿瘤。其发展可导致退行性改变,偶尔在影像学上类似恶性肿瘤,带来诊断挑战。

病例报告

一名31岁未生育女性出现腹胀、绞痛和腹部膨隆症状。影像学检查提示晚期卵巢恶性肿瘤,显示附件区有复杂包块且CA - 125水平升高。在剖腹探查术中,病理评估显示疑似卵巢癌的病变实际上是一个大的子宫包块,为伴有广泛水样变性的良性平滑肌瘤。

结论

本病例突出了与大型复杂附件包块相关的诊断复杂性,并说明了诸如伴有水样变性的平滑肌瘤等良性病变如何能酷似卵巢癌。这强调了全面的术前和术中评估对于制定治疗方案及避免不必要的根治性手术的重要性。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bcc2/11126525/4eca0f2cae70/gr1.jpg

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