Medical Intensive Care Unit, Ibn El Jazzar University Hospital, Kairouan, Tunisia.
Pulmonology Department, Ibn El Jazzar University Hospital, Kairouan, Tunisia.
Pan Afr Med J. 2024 Feb 27;47:92. doi: 10.11604/pamj.2024.47.92.34766. eCollection 2024.
Indoxacarb, a large-spectrum non-organophosphorus oxadiazine insecticide, is broadly used in farming whose mechanism of action is the blockage of voltage-gated sodium channels of insects. There is restricted data on human poisoning. We report a case of an 18-year-old male patient without comorbidities presented with unconsciousness and cyanosis after the intentional ingestion of indoxacarb in a suicide attempt. Methemoglobinemia was clinically suspected and was successfully treated after methylene blue injection, associated with supportive and symptomatic management. This case emphasizes the importance of considering methemoglobinemia after indoxacarb ingestion in addition to its early recognition and timely injection of methylene blue which led to complete recovery without sequelae.
茚虫威，一种广谱非有机磷噁二嗪杀虫剂，广泛应用于农业，其作用机制是阻断昆虫的电压门控钠离子通道。关于人类中毒的资料有限。我们报告了一例 18 岁男性患者，无合并症，在自杀企图中故意摄入茚虫威后出现意识丧失和发绀。临床上怀疑为高铁血红蛋白血症，并成功地通过注射亚甲蓝治疗，同时给予支持和对症治疗。该病例强调了在摄入茚虫威后除了早期识别和及时注射亚甲蓝外，还应考虑高铁血红蛋白血症的重要性，这导致患者完全康复，没有后遗症。
