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使用不同膜进行血液透析期间外周血淋巴细胞的细胞电泳研究。

Cell electrophoretic investigations of peripheral blood lymphocytes during hemodialysis with different membranes.

作者信息

Thomaneck U, Falkenhagen D, Brown G S, Schütt W, Travers M, Klinkmann H

机构信息

Wilhelm Pieck University of Rostock, Dept. of Internal Med., GDR.

出版信息

Life Support Syst. 1985;3 Suppl 1:53-7.

PMID:3879955
Abstract

Determining the relative percentage of LMC in PBL histograms of RDT patients during hemodialysis we observed a temporary decrease of the LMC proportion during the first 15 minutes of hemodialysis using Cuprophan in contrast to AN 69S and MC Cellulose. These results correlate with the increase of C3a plasma concentration and the decrease of total count of granulocytes. In all investigated RDT patients higher proportions of LMC could be found in relation to healthy donors already before dialysis treatment. Our study therefore seems to indicate that the application of cell electrophoresis is a useful method for the characterization of lymphocytes during extracorporeal circulation as an additional parameter of blood compatibility.

摘要

在确定血液透析期间RDT患者的PBL直方图中LMC的相对百分比时,我们观察到,与AN 69S和MC纤维素相比,使用铜仿膜进行血液透析的前15分钟内LMC比例暂时下降。这些结果与C3a血浆浓度的增加和粒细胞总数的减少相关。在所有接受调查的RDT患者中,甚至在透析治疗前,与健康供体相比,LMC的比例就更高。因此,我们的研究似乎表明,细胞电泳的应用是一种用于在体外循环期间表征淋巴细胞的有用方法,可作为血液相容性的一个附加参数。

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