Wu Jingxuan, Zhang Wenzhu, Zhang Hong, Lu Xingjia, Luan Biqing, Yang Qizhi, Chen Liang, Chen Wenlin, Ge Fei
Department of Breast Surgery, First Affiliated Hospital of Kunming Medical University, Kunming, 650000, People's Republic of China.
No. 1 School of Clinical Medicine, Kunming Medical University, Kunming, 650000, People's Republic of China.
Onco Targets Ther. 2024 May 23;17:411-419. doi: 10.2147/OTT.S456532. eCollection 2024.
Breast cancer is one of the most common malignant tumors affecting women worldwide. Breast cancer is a complex disease characterized by abnormal growth of cells in the breast tissue. Metastasis, the spread of cancer cells from the primary tumor site to distant organs, is a major challenge in the management of breast cancer. Although metastasis to distant sites is a well-known feature of breast cancer, scalp involvement is relatively rare. The occurrence of scalp metastasis signifies an advanced stage of the disease. The 51-year-old female discovered a firm, painless mass in her right breast that had been there for two years. It had been pricking for a month, and the biopsy revealed that the mass was invasive carcinoma of the right breast. Imaging tests suggested that the tumor was malignant. Adjuvant endocrine therapy and postoperative adjuvant chemotherapy were administered following a modified radical resection for breast cancer. Eleven months later, radiation treatment and replace endocrine therapy was used. 32 months following surgery, a scalp tumor was discovered; a pathology biopsy verified the origin of the breast cancer; three months later, bone, brain, and visceral metastases were discovered. After that, she received oral capecitabine treatment and was admitted into the hospital for advanced rescue treatment. She is currently in the disease stability state, her disease is effectively managed, and no new metastatic lesions have been discovered.
乳腺癌是全球影响女性的最常见恶性肿瘤之一。乳腺癌是一种复杂的疾病,其特征是乳腺组织中细胞异常生长。转移,即癌细胞从原发肿瘤部位扩散到远处器官,是乳腺癌治疗中的一个主要挑战。虽然远处转移是乳腺癌的一个众所周知的特征,但头皮受累相对罕见。头皮转移的发生表明疾病已处于晚期。这位51岁的女性在其右乳发现一个坚硬、无痛的肿块,已经存在两年了。它刺痛了一个月,活检显示该肿块为右乳浸润性癌。影像学检查表明该肿瘤为恶性。在对乳腺癌进行改良根治性切除术后,给予辅助内分泌治疗和术后辅助化疗。11个月后,采用了放射治疗和替代内分泌治疗。术后32个月,发现头皮肿瘤;病理活检证实为乳腺癌转移;三个月后,发现骨、脑和内脏转移。此后,她接受了口服卡培他滨治疗,并因晚期抢救治疗入院。她目前处于疾病稳定状态,病情得到有效控制,未发现新的转移病灶。