Flach A J, Dolan B J
Department of Opthalmology, University of California, San Francisco.
J Ocul Pharmacol. 1985 Winter;1(4):353-62. doi: 10.1089/jop.1985.1.353.
Impressed by the benefit two patients with Adie's Syndrome derived from topical 0.1% pilocarpine therapy, we performed the present study to examine the measurable effects of 0.1% pilocarpine in several patients with this syndrome. Our study suggests those patients with Adie's Syndrome who lack stereoacuity may benefit from long term therapy with dilute pilocarpine if their stereoacuity may benefit from long term therapy with dilute pilocarpine if their stereoacuity improves following a single drop of 0.1% pilocarpine. Therefore, we recommend measuring stereoacuity during pupil diagnostic testing with 0.1% pilocarpine hydrochloride. Potential problems concerning medical therapy of Adie's Syndrome with parasympathomimetics are discussed.
两名患有阿狄氏综合征的患者从局部使用0.1%毛果芸香碱治疗中获益，这给我们留下了深刻印象，因此我们开展了本研究，以检验0.1%毛果芸香碱对该综合征若干患者的可测量疗效。我们的研究表明，那些缺乏立体视锐度的阿狄氏综合征患者，如果在滴入一滴0.1%毛果芸香碱后立体视锐度得到改善，那么长期使用稀释的毛果芸香碱治疗可能会使其受益。因此，我们建议在使用0.1%盐酸毛果芸香碱进行瞳孔诊断测试时测量立体视锐度。文中还讨论了使用拟副交感神经药治疗阿狄氏综合征可能存在的问题。
