School of Primary and Allied Health Care, Monash University, 47-49 Moorooduc Hwy, Frankston, VIC, 3199, Australia.
Ablefeet, 16 Terrace Road, Walton-on-Thames, Surrey, KT12 2SB, UK.
Eur J Pediatr. 2024 Aug;183(8):3517-3529. doi: 10.1007/s00431-024-05621-4. Epub 2024 May 27.
Current international consensus of the appropriate Beighton score cut-off to define if a child has generalised joint hypermobile or not is based upon expert opinion. Our aim was to determine the prevalence of Beighton scores of children worldwide to provide a recommendation for establishing the Beighton score cut-off to identify generalised joint hypermobility in children. We used AMED, OVID Medline, Embase and CINAHL to find published articles from inception to April 2024 describing Beighton scores of children up to and including 18 years from the general population. We extracted study demographics including country of publication, total number of participants, summary data about the age and sex of participant, Beighton scores and any cut-off used where authors deemed children hypermobile and how many children were rated at the corresponding Beighton scores. There were 37 articles reporting on the prevalence or incidence of hypermobility at cut-off scores from 28,868 participants. Using the cut-off of ≥ 6 resulted in a prevalence of 6% for studies reporting male data and 13% for studies reporting female data. Limited data reporting availability precluded further sub-analysis at a Beighton score of ≥ 7, age, pubertal status and ethnicity. Conclusion: The working threshold for identifying generalised joint hypermobility in children should be a Beighton score of 6 or more. Our analysis also suggests a Beighton score of 7 or greater may be appropriate in childhood, particularly for females. What is Known: • The working threshold for identifying generalised joint hypermobility in children previously was set based on expert opinion. What is New: • The threshold to identify hypermobility in children should be at a minimum of ≥ 6 on the Beighton score.
目前，国际上对于定义儿童是否患有全身性关节过度活动的适当 Beighton 评分截断值，是基于专家意见的共识。我们的目的是确定全球儿童的 Beighton 评分流行率，以便为确定 Beighton 评分截断值以识别儿童全身性关节过度活动提供建议。我们使用 AMED、OVID Medline、Embase 和 CINAHL 来查找截至 2024 年 4 月发表的描述一般人群中 18 岁以下儿童 Beighton 评分的文章。我们提取了研究人口统计学数据，包括出版国家、参与者总数、参与者年龄和性别、Beighton 评分以及作者认为儿童具有过度活动性的任何截断值，以及被评为相应 Beighton 评分的儿童人数。有 37 篇文章报告了在 28,868 名参与者中使用截断值的过度活动性的流行率或发病率。使用截断值≥6 的结果是，报告男性数据的研究的流行率为 6%，报告女性数据的研究的流行率为 13%。由于缺乏数据报告，进一步在 Beighton 评分≥7、年龄、青春期状态和种族方面进行亚分析是不可能的。结论：确定儿童全身性关节过度活动的工作阈值应为 Beighton 评分≥6。我们的分析还表明，Beighton 评分≥7 在儿童中可能更为合适，特别是对于女性。已知的：• 以前，确定儿童全身性关节过度活动的工作阈值是基于专家意见。新的内容：• 确定儿童过度活动性的阈值至少应为 Beighton 评分≥6。
