Schweiger H G
Arzneimittelforschung. 1978;28(10a):1814-8.
Monocellular organisms are well suited for studies on the molecular mechanisms of circadian rhythms. Thythms in different monocellular organisms are similar. This mean that it might be anticipated that the mechanisms of all these rhythms are similar. Evidence so far available has resulted in several models, some of which emphasize the role of membranes and deserve special interest. A "coupled translation membrane model" is in full agreement with those particular results which have been obtained on the green alga, Acetabularia. Attempts to verify the role of essential polypeptides which was postulated in the model, by isolating such components appear to be successful.
单细胞生物非常适合用于昼夜节律分子机制的研究。不同单细胞生物中的节律是相似的。这意味着可以预期所有这些节律的机制都是相似的。目前已有的证据产生了几种模型,其中一些强调了膜的作用,值得特别关注。“耦合翻译膜模型”与在绿藻伞藻上获得的那些特定结果完全一致。通过分离此类成分来验证该模型中假定的必需多肽的作用的尝试似乎是成功的。