Stawowski Aleksander Robert, Konopińska Joanna, Stawowski Sylwester Szymon, Adamczuk Justyna, Groth Monika, Moniuszko-Malinowska Anna, Czupryna Piotr
Department of Ophthalmology, University Clinical Hospital in Bialystok, Bialystok, Poland.
Department of Ophthalmology, Medical University of Bialystok, Bialystok, Poland.
Clin Ophthalmol. 2024 May 23;18:1417-1432. doi: 10.2147/OPTH.S460224. eCollection 2024.
The COVID-19 pandemic caused by SARS-CoV-2 had a significant impact on the health of the global human population, affecting almost every human organ, including the organ of vision. Research focus on understanding the pathophysiology, identifying symptoms and complications of the disease. Eye-related pathologies are important foci of research due to the potential for direct impact of the virus. Ophthalmologists around the world are reporting various symptoms of eye infections and ocular pathologies associated with SARS-CoV-2. The review of ophthalmic symptoms was conducted to help physicians of various specialties recognize possible ophthalmic manifestations of this viral disease. A literature review was conducted from January 2020 to July 2023 in the PubMed, MEDLINE, Science Direct, Scopus, Scielo and Google Scholar databases. The review of the literature showed that conjunctivitis is the most common ophthalmic symptom observed during the course of COVID-19 and can occur at any stage of the disease. Changes in the eye may result from the direct effect of the virus, immune response, prothrombotic states, comorbidities, and medications used. Symptoms related to the organ of vision can be divided into: changes affecting the protective apparatus of the eye, the anterior eye segment, the posterior eye segment, neuro-ophthalmic, and orbital changes. Ocular symptoms may suggest COVID-19 infection or appear several weeks after recovery. Following COVID-19 vaccinations, a diverse range of ophthalmic symptoms was observed in various locations and at different times, mirroring the ocular symptoms experienced throughout the course of the COVID-19 illness. It is important for physicians of all specialties to be aware of possible potential connections between eye diseases and SARS-CoV-2, in order to effectively diagnose and treat patients.
由严重急性呼吸综合征冠状病毒2（SARS-CoV-2）引起的2019冠状病毒病大流行对全球人类健康产生了重大影响，几乎影响到每个人体器官，包括视觉器官。研究重点在于了解该疾病的病理生理学、识别症状和并发症。由于病毒可能产生直接影响，与眼睛相关的病理学是重要的研究焦点。世界各地的眼科医生报告了与SARS-CoV-2相关的各种眼部感染症状和眼部病理学情况。对眼科症状进行综述，以帮助各专科医生识别这种病毒性疾病可能的眼部表现。于2020年1月至2023年7月在PubMed、MEDLINE、科学Direct、Scopus、Scielo和谷歌学术数据库中进行了文献综述。文献综述表明，结膜炎是在2019冠状病毒病病程中观察到的最常见眼科症状，可发生在疾病的任何阶段。眼睛的变化可能由病毒的直接作用、免疫反应、血栓前状态、合并症和所用药物引起。与视觉器官相关的症状可分为：影响眼睛保护装置、眼前节、眼后节、神经眼科和眼眶的变化。眼部症状可能提示2019冠状病毒病感染，或在康复后数周出现。在接种2019冠状病毒病疫苗后，在不同地点和不同时间观察到了各种各样的眼科症状，这与2019冠状病毒病病程中出现的眼部症状相似。所有专科医生都应了解眼部疾病与SARS-CoV-2之间可能存在的潜在联系，以便有效地诊断和治疗患者。
