Lacey D J
Department of Neurology, State University of New York, Buffalo.
Pediatr Neurol. 1985 Mar-Apr;1(2):100-3. doi: 10.1016/0887-8994(85)90044-x.
Localization of brain injury to parasagittal arterial border zones in the asphyxiated term neonate has been recently described as a frequent, clinically significant finding. However, pathologic examination of the brains of 79 term infants did not reveal a parasagittal distribution of damage. Coronal CT scans of 13 asphyxiated neonates with clinical findings of proximal hypotonia, and repeat scans 6-12 months later in seven patients, have not demonstrated watershed areas of decreased density. A larger series of prospectively identified, surviving neonates is needed to determine whether clinically relevant parasagittal injury may be present in this population.
近期研究表明,足月窒息新生儿脑损伤定位于矢状旁动脉边缘区是一种常见且具有临床意义的发现。然而,对79例足月婴儿的脑部进行病理检查,并未发现损伤呈矢状旁分布。对13例有近端肌张力减退临床表现的窒息新生儿进行冠状位CT扫描,并对其中7例患者在6 - 12个月后进行重复扫描,均未发现密度降低的分水岭区域。需要对更多前瞻性确定的存活新生儿进行研究,以确定该人群中是否可能存在具有临床相关性的矢状旁损伤。